P3245 Induction of bradykinin type-I receptor expression in the left ventricle of patients with end-stage heart failure

2003 ◽  
Vol 24 (5) ◽  
pp. 612
Author(s):  
I LIESMAA
1998 ◽  
Vol 30 (3) ◽  
pp. 443-451 ◽  
Author(s):  
Guojie Song ◽  
Begoña Campos ◽  
Lynne E Wagoner ◽  
John R Dedman ◽  
Richard A Walsh

2002 ◽  
Vol 40 (1) ◽  
pp. 119-125 ◽  
Author(s):  
Antti Kuoppala ◽  
Naotaka Shiota ◽  
Jorma O Kokkonen ◽  
Inka Liesmaa ◽  
Karam Kostner ◽  
...  

Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).


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