A variable-number-tandem-repeat of the serotonin transporter gene and anxiety disorders

1999 ◽  
Vol 23 (1) ◽  
pp. 55-65 ◽  
Author(s):  
Koichi Ohara ◽  
Yasuo Suzuki ◽  
Masato Ochiai ◽  
Toshio Tsukamoto ◽  
Kunihiko Tani ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Serotonin Transporter ◽  
Tandem Repeat ◽  
Variable Number Tandem Repeat ◽  
Variable Number ◽  
Serotonin Transporter Gene ◽  
Transporter Gene

scholarly journals Neuroticism and polymorphisms in the serotonin transporter gene

1999 ◽  
Vol 29 (3) ◽  
pp. 735-739 ◽  
Author(s):  
I. J. DEARY ◽  
S. BATTERSBY ◽  
M. C. WHITEMAN ◽  
J. M. CONNOR ◽  
F. G. R. FOWKES ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
Personality Trait ◽  
Gene Polymorphisms ◽  
Haplotype Analysis ◽  
Variable Number Tandem Repeat ◽  
Variable Number ◽  
Serotonin Transporter Gene ◽  
Transporter Gene ◽  
Tandem Repeat Region ◽  
Significant Linkage

Background. There is evidence for an association between two different polymorphisms of the human serotonin transporter gene (5-HTT) and the personality trait of neuroticism and affective disorder.Methods. We studied the association between neuroticism and polymorphisms in the 5HTT-linked promoter region and in a variable number tandem repeat region (VNTR) of the 5-HTT gene in 204 people aged over 60 derived from a random sample of men and women in the general population. Approximately half of the subjects were in the top 20% of neuroticism scorers and half in the bottom 20%.Results. There were no significant differences in allelic or genotypic frequencies between the high and low neuroticism scorers. There was highly significant linkage disequilibrium between the two 5-HTT gene polymorphisms, and haplotype analysis showed no association between neuroticism level and haplotype.Conclusions. Reports of an association between two 5-HTT gene polymorphisms and the personality trait of neuroticism are not supported by these results.

scholarly journals Combinatorial interaction between two human serotonin transporter gene variable number tandem repeats and their regulation by CTCF

2010 ◽  
Vol 112 (1) ◽  
pp. 296-306 ◽  
Author(s):  
Fahad R. Ali ◽  
Sylvia A. Vasiliou ◽  
Kate Haddley ◽  
Ursula M. Paredes ◽  
Julian C. Roberts ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
Tandem Repeats ◽  
Variable Number ◽  
Serotonin Transporter Gene ◽  
Transporter Gene ◽  
Variable Number Tandem Repeats

Working conditions, serotonin transporter gene polymorphism (5-HTTLPR) and anxiety disorders: A prospective cohort study

2013 ◽  
Vol 151 (2) ◽  
pp. 652-659 ◽  
Author(s):  
Bojing Liu ◽  
Catharina Lavebratt ◽  
Tobias Nordqvist ◽  
Andrés Fandiño-Losada ◽  
Töres Theorell ◽  
...  
Keyword(s):  
Cohort Study ◽  
Gene Polymorphism ◽  
Anxiety Disorders ◽  
Serotonin Transporter ◽  
Prospective Cohort Study ◽  
Working Conditions ◽  
Prospective Cohort ◽  
Serotonin Transporter Gene ◽  
Transporter Gene

Association between anxiety disorders and a functional polymorphism in the serotonin transporter gene

1998 ◽  
Vol 81 (2) ◽  
pp. 277-279 ◽  
Author(s):  
Koichi Ohara ◽  
Miho Nagai ◽  
Yasuo Suzuki ◽  
Masato Ochiai ◽  
Kenshiro Ohara
Keyword(s):  
Anxiety Disorders ◽  
Serotonin Transporter ◽  
Serotonin Transporter Gene ◽  
Functional Polymorphism ◽  
Transporter Gene

Anxiety disorders and anxiety-related traits and serotonin transporter gene-linked polymorphic region (5-HTTLPR) in adolescents

2014 ◽  
Vol 24 (4) ◽  
pp. 176-180 ◽  
Author(s):  
Andressa Bortoluzzi ◽  
Carolina Blaya ◽  
Giovanni A. Salum ◽  
Carolina Cappi ◽  
Sandra Leistner-Segal ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Serotonin Transporter ◽  
Serotonin Transporter Gene ◽  
Transporter Gene ◽  
Polymorphic Region
Sign in / Sign up

Export Citation Format

Share Document