Functional dyspepsia has a good prognosis irrespective of H. pylori status Long-term follow-up of symptoms after anti H. pylori treatment

1999 ◽  
Vol 55 (2) ◽  
pp. 64-70 ◽  
Author(s):  
B Werdmuller
2001 ◽  
Vol 120 (5) ◽  
pp. A754-A755 ◽  
Author(s):  
H ALLESCHER ◽  
P ENCK ◽  
G ADLER ◽  
R DIETL ◽  
J HARTUNG ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Juliana Gabriel Ribeiro de Andrade ◽  
Antonia Paula Marques-de-Faria ◽  
Helena Campos Fabbri ◽  
Maricilda Palandi de Mello ◽  
Gil Guerra-Júnior ◽  
...  

Background/Aims. Studies on 46,XY partial gonadal dysgenesis (PGD) have focused on molecular, gonadal, genital, and hormone features; little is known about follow-up. Our aim was to analyze long-term outcomes of PGD.Methods. Retrospective longitudinal study conducted at a reference service in Brazil. Ten patients were first evaluated in the 1990s and followed up until the 2010s; follow-up ranged from 13.5 to 19.7 years. All were reared as males and had at least one scrotal testis; two boreNR5A1mutations. Main outcomes were: associated conditions, pubertal development, and growth.Results. All patients had normal motor development but three presented cognitive impairment; five had various associated conditions. At the end of the prepubertal period, FSH was high or high-normal in 3/6 patients; LH was normal in all. At the last evaluation, FSH was high or high-normal in 8/10; LH was high or high-normal in 5/10; testosterone was decreased in one. Final height in nine cases ranged from −1.57 to 0.80 SDS. All had spontaneous puberty; only one needed androgen therapy.Conclusions. There is good prognosis for growth and spontaneous pubertal development but not for fertility. Though additional studies are required, screening for learning disabilities is advisable.


2011 ◽  
Vol 43 (4) ◽  
pp. 295-299 ◽  
Author(s):  
Lucy Vannella ◽  
Edith Lahner ◽  
Cesare Bordi ◽  
Emanuela Pilozzi ◽  
Emilio Di Giulio ◽  
...  
Keyword(s):  

2001 ◽  
Vol 120 (5) ◽  
pp. A754-A755
Author(s):  
Hans-Dieter Allescher ◽  
Paul Enck ◽  
Guido Adler ◽  
Rolf Dietl ◽  
Joachim Hartung ◽  
...  

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 5016-5016
Author(s):  
P. S. Grimison ◽  
M. R. Stockler ◽  
D. B. Thomson ◽  
I. N. Olver ◽  
V. J. Harvey ◽  
...  

5016 Background: We performed a multicentre randomised trial for good-prognosis germ-cell tumours of two standard chemotherapy regimens containing bleomycin (B), etoposide (E) and cisplatin (P). Accrual was stopped early, after interim analysis with a median follow-up of 33 months found a survival benefit for the regimen similar to Indiana University BEP, compared with the less dose-intense regimen (Toner, Lancet 2001). Here we report on long-term outcomes and patterns of relapse. Methods: Patients with a good prognosis defined by modified Memorial Sloan-Kettering criteria were randomised to 3B90E500P (3 cycles every 21 days of B 30 kU on days 1, 8 and 15, E 100 mg/m2 on days 1–5, and P 20 mg/m2 on days 1–5); or 4B30E360P (4 cycles every 21 days of B 30 kU on day 1, E 120 mg/m2 on days 1–3, and P 100 mg/m2 on day 1). Overall survival was the primary endpoint. Progression-free survival (PFS) was a secondary endpoint. All analyses were by intention-to-treat and with 2-sided p-values. Results: 166 patients were randomised, 83 to each regimen. Median follow-up is now 8.5 years and all but 5 have been followed ≥ 5 years. Overall survival remains substantially better with 3B90E500P than 4B30E360P (8YS 92% vs 83%, hazard ratio 0.38, 95% CI 0.15 to 0.97, p=0.037), and remains significant when analyses were restricted to 138 patients with good prognosis by IGCCCG criteria (p=0.035). Trends for PFS favour 3B90E500P but are not statistically significant (8YPFS 86% vs 79%, hazard ratio 0.6, 95% CI 0.3 to 1.1, p=0.15). 7 of 15 relapses occurring within 2 years after randomisation were fatal, but all 4 relapses occurring > 2 years after randomisation were fatal. Conclusions: The survival benefit of 3B90E500P compared to 4B30E360P was maintained with long-term follow-up. The occurrence of relapses beyond 2 years affirms the importance of long-term follow-up. Late relapses in this study were associated with uniformly poor outcomes. [Table: see text] No significant financial relationships to disclose.


2021 ◽  
Vol 8 ◽  
Author(s):  
Long Song ◽  
Chukwuemeka Daniel Iroegbu ◽  
Jinfu Yang ◽  
Chengming Fan

Cardiac lipomas, though extremely rare, are encapsulated tumors composed primarily of mature fat cells. Despite their benign character, cardiac lipomas can cause life-threatening complications by rapid growth. Cardiac lipomas, which are frequently located in the left ventricle (LV) or right atrium, can originate either from the subendocardium, subpericardium, or the myocardium. They are usually asymptomatic and carry a good prognosis during long-term follow-up; however, published reports show that untreated cardiac lipomas may be fatal when they cause arrhythmic or obstructive symptoms. In addition, several surgical options have been reported to obtain an appropriate operative view following poor visualization, primarily when tumors are located in the LV. Herein, we present a case of a pedunculated LV apical lipoma in a symptomatic patient successfully managed by surgical resection. We also discuss diagnostic modalities in surgical planning and the choice of surgical approach.


2019 ◽  
Vol 8 (1) ◽  
pp. 5
Author(s):  
Joham Choque-Velasquez ◽  
Julio C Resendiz-Nieves ◽  
Behnam Rezai Jahromi ◽  
Roberto Colasanti ◽  
Rahul Raj ◽  
...  

Background: Pineocytomas are rare benign lesions with a relatively good prognosis if gross total resection can be achieved. Report of cases: We present a retrospective review of four patients with histologically confirmed pineocytomas consecutively operated on after 1997. All of our patients were alive at a mean follow-up of 224,5 months (range 204-246). A gross total resection was accomplished in all cases. The cornerstones for the surgical resection of pineocytomas are reported. Conclusions: A proper management of pineocytomas, based on the gross total microsurgical resection of the lesion, results in an excellent long term outcome of these pineal lesions.


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