Characterization of the molecular motions of constitutively active G protein-coupled receptors for parathyroid hormone

2001 ◽  
Vol 89 (2-3) ◽  
pp. 119-128 ◽  
Author(s):  
Christian Rölz ◽  
Dale F. Mierke
Keyword(s):  
Parathyroid Hormone ◽  
G Protein ◽  
G Protein Coupled Receptors ◽  
Molecular Motions ◽  
G Protein Coupled ◽  
Constitutively Active

Proteinase-Activated Receptors: New Functions for Old Enzymes

Physiology ◽  
1998 ◽  
Vol 13 (5) ◽  
pp. 231-240 ◽  
Author(s):  
Stephan K. Böhm ◽  
Karen McConalogue ◽  
Wuyi Kong ◽  
Nigel W. Bunnett
Keyword(s):  
G Protein ◽  
Signaling Molecules ◽  
G Protein Coupled Receptors ◽  
Proteinase Activated Receptors ◽  
Degradative Enzymes ◽  
G Protein Coupled

Although proteases are traditionally viewed as degradative enzymes, characterization of a family of G protein-coupled receptors that are activated by proteolysis reveals a new role. Certain proteases function as signaling molecules that specifically regulate cells by cleaving and activating a family of proteinase-activated receptors.

Constitutively Active Mutations of G Protein-Coupled Receptors

1999 ◽  
Vol 30 (6) ◽  
pp. 501-509 ◽  
Author(s):  
Verena Nordhoff ◽  
Jörg Gromoll ◽  
Manuela Simoni
Keyword(s):  
G Protein ◽  
G Protein Coupled Receptors ◽  
G Protein Coupled ◽  
Constitutively Active
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