Proteinase-Activated Receptors: New Functions for Old Enzymes

Physiology ◽  
1998 ◽  
Vol 13 (5) ◽  
pp. 231-240 ◽  
Author(s):  
Stephan K. Böhm ◽  
Karen McConalogue ◽  
Wuyi Kong ◽  
Nigel W. Bunnett
Keyword(s):  
G Protein ◽  
Signaling Molecules ◽  
G Protein Coupled Receptors ◽  
Proteinase Activated Receptors ◽  
Degradative Enzymes ◽  
G Protein Coupled

Although proteases are traditionally viewed as degradative enzymes, characterization of a family of G protein-coupled receptors that are activated by proteolysis reveals a new role. Certain proteases function as signaling molecules that specifically regulate cells by cleaving and activating a family of proteinase-activated receptors.

In-vitro folding and functional characterization of the extracellular domain of G protein-coupled receptors

2002 ◽  
Vol 30 (3) ◽  
pp. A60-A60
Author(s):  
A. Kuntzsch ◽  
U. Grauschopf ◽  
A. Bazarsuren ◽  
K. Wenig ◽  
H. Lilie ◽  
...  
Keyword(s):  
G Protein ◽  
Functional Characterization ◽  
Extracellular Domain ◽  
G Protein Coupled Receptors ◽  
G Protein Coupled

scholarly journals Identification and Functional Characterization of Two Orphan G-protein-coupled Receptors for Adipokinetic Hormones from SilkwormBombyx mori

2011 ◽  
Vol 286 (49) ◽  
pp. 42390-42402 ◽  
Author(s):  
Ying Shi ◽  
Haishan Huang ◽  
Xiaoyan Deng ◽  
Xiaobai He ◽  
Jingwen Yang ◽  
...  
Keyword(s):  
G Protein ◽  
Functional Characterization ◽  
G Protein Coupled Receptors ◽  
G Protein Coupled
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