Reversed-phase ion-pair liquid chromatographic method for the determination of low concentrations of haloperidol in plasma

Author(s):  
Lars B. Nilsson
1995 ◽  
Vol 78 (5) ◽  
pp. 1131-1133
Author(s):  
Alan R Hanks

Abstract A liquid chromatographic method for determination of dithianon in technical products and formulations was evaluated by 22 laboratories participating in a collaborative study. Data received from 19 laboratories were used in the statistical analysis. The study included 3 technical grade materials, 1 suspension concentrate, and 1 wettable powder. Dithianon is determined by reversed-phase liquid chromatography on a C18 column with a mobile phase of acetonitrile and water. Detection at 254 nm with peak area measurements is used with an external standard for quantitation of dithianon. The liquid chromatographic method for determination of dithianon in technical products and formulations has been adopted first action by AOAC INTERNATIONAL.


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