Application of attenuated total reflectance Fourier transform infrared spectrometry to the determination of cephalosporin C in complex fermentation broths

2003 ◽  
Vol 31 (3) ◽  
pp. 571-577 ◽  
Author(s):  
K Kargosha ◽  
M Khanmohammadi ◽  
M Sarokhani ◽  
F Ansari ◽  
M Ghadiri
Keyword(s):  
Fourier Transform ◽  
Fourier Transform Infrared ◽  
Attenuated Total Reflectance ◽  
Infrared Spectrometry ◽  
Cephalosporin C ◽  
Fourier Transform Infrared Spectrometry ◽  
Total Reflectance ◽  
Fermentation Broths

Fourier Transform Infrared Spectrometry/Attenuated Total Reflectance Study of the Reaction of Pentanal and Propanal with 2-(Hydroxymethyl)Piperidine

1992 ◽  
Vol 46 (2) ◽  
pp. 266-272 ◽  
Author(s):  
Eugene R. Kennedy ◽  
Kevin Ashley
Keyword(s):  
Fourier Transform ◽  
Fourier Transform Infrared ◽  
Solution Phase ◽  
Attenuated Total Reflectance ◽  
Infrared Spectrometry ◽  
Fourier Transform Infrared Spectrometry ◽  
Total Reflectance ◽  
Solid Interface ◽  
Ft Ir ◽  
Flow Through

The reactions of propanal and pentanal with 2-(hydroxymethyl)piperidine were investigated by Fourier transform infrared spectrometry/attenuated total reflectance in both the solution phase and at the gas/solid interface. The reactions were studied with the use of a flow-through cylindrical internal reflection (“circle”) cell. Reaction intermediates were tentatively identified by their characteristic infrared absorption frequencies. At the gas/solid interface the reaction is thought to yield a hemiaminal intermediate. In the solution phase a hemiaminal intermediate is believed to form initially, followed by loss of water to generate an enamine product. In both gas-phase and solution-phase studies, an oxazolidine product is prepared only after an ultrasound treatment. The FT-IR/ATR technique reveals detailed mechanistic information concerning reactions between aldehydes and ethanol amines.

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