Spectrophotometric determination of loperamide hydrochloride by acid-dye and charge-transfer complexation methods in the presence of its degradation products

2000 ◽  
Vol 22 (1) ◽  
pp. 13-23 ◽  
Author(s):  
Z.A. El Sherif ◽  
A.O. Mohamed ◽  
M.I. Walash ◽  
F.M. Tarras
The Analyst ◽  
1984 ◽  
Vol 109 (11) ◽  
pp. 1417 ◽  
Author(s):  
Magda M. Ayad ◽  
Saied Belal ◽  
Sobhi M. El Adl ◽  
Afaf A. Al Kheir

2018 ◽  
Vol 6 (4) ◽  
pp. 65-71
Author(s):  
B. Eswara Naik ◽  
C. Narasimha Rao ◽  
S. Ramanaiah ◽  
P. Venkateswarlu

2010 ◽  
Vol 3 (1) ◽  
pp. 207
Author(s):  
C. J. Mbah ◽  
N. H. Okorie

A spectrophotometric study of chlorpropamide is described. The method is based on the charge-transfer complexation between chlorpropamide (the n-electron donor) with chloranilic acid (the p-acceptor) to form a violet coloured complex having absorption maxima at 530 nm. Beer’s law is obeyed for up to 5-25 mg/ml of chlorpropamide. Results of the analysis of this method were validated statistically by recovery studies. The proposed method is simple, accurate and precise for the quantitative determination of chlorpropamide in bulk and tablet formulations.Keywords: Chlorpropamide; Spectrophotometry; Chloranilic acid.© 2011 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi:10.3329/jsr.v3i1.4808                 J. Sci. Res. 3 (1), 207-212 (2011)


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