scholarly journals Therapy with the acorn cardiac support device reduces mRNA expression of brain and atrial natriuretic peptides in left ventricular myocardium of dogs with heart failure

2002 ◽  
Vol 39 ◽  
pp. 140-141
Author(s):  
Sharad Rastogi ◽  
Ramesh C. Gupta ◽  
Sudhish Mishra ◽  
George Suzuki ◽  
Hideaki Morita ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mrna Expression ◽  
Natriuretic Peptides ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Left Ventricular Myocardium ◽  
Atrial Natriuretic Peptides ◽  
Support Device ◽  
Cardiac Support Device ◽  
Atrial Natriuretic

scholarly journals Relation of atrial natriuretic peptides to left ventricular systolic and diastolic function in heart failure

1999 ◽  
Vol 1 (1) ◽  
pp. 51-58 ◽  
Author(s):  
Anke A.M. Wijbenga ◽  
Aggie H.M.M. Balk ◽  
Fokke A.M. Jonkman ◽  
Frans Boomsma ◽  
Maarten L. Simoons ◽  
...  
Keyword(s):  
Heart Failure ◽  
Diastolic Function ◽  
Natriuretic Peptides ◽  
Left Ventricular ◽  
Atrial Natriuretic Peptides ◽  
Systolic And Diastolic Function ◽  
Atrial Natriuretic

scholarly journals Gene expression of adrenomedullin in failing myocardium: comparison to atrial natriuretic peptide

2002 ◽  
Vol 92 (3) ◽  
pp. 1058-1063 ◽  
Author(s):  
Anselm T. Bäumer ◽  
Christina Schumann ◽  
Bodo Cremers ◽  
Gabi Itter ◽  
Wolfgang Linz ◽  
...  
Keyword(s):  
Heart Failure ◽  
Dilated Cardiomyopathy ◽  
Normal Subjects ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Human Myocardium ◽  
Idiopathic Dilated Cardiomyopathy ◽  
Left Ventricular Myocardium ◽  
End Stage ◽  
Atrial Natriuretic

The expression of adrenomedullin (AM) and atrial natriuretic factor (ANF) were investigated in the myocardium of a rat model of chronic ischemic heart failure (CHF) compared with sham-operated controls. In addition, human myocardium of patients with end-stage heart failure due to idiopathic dilated cardiomyopathy compared with myocardium of normal subjects (NF) was studied. In CHF, similar AM levels but increased ANF expression were observed in left ventricular myocardium, as assessed by semiquantitative PCR. Functional experiments with freshly excised papillary muscles showed no influence of AM on myocardial contractility. In NF human myocardium, the expression of AM mRNA was threefold higher in atrial compared with ventricular tissue. In analogy, ANF mRNA was increased by ∼15-fold in atrial tissue. In dilated cardiomyopathy, the expression of AM was significantly increased in right and left ventricles compared with NF. In parallel, ventricular ANF expression was enhanced.

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