THE ASSOCIATION OF LEFT VENTRICULAR FILLING, LEFT ATRIAL DYNAMICS, AND STIFFNESS WITH RIGHT VENTRICULAR TO PULMONARY CIRCULATION UNCOUPLING DURING EXERCISE IN PATIENTS WITH LEFT HEART DISEASE

2019 ◽  
Vol 73 (9) ◽  
pp. 1499
Author(s):  
Tadafumi Sugimoto ◽  
Francesco Bandera ◽  
Sara Boveri ◽  
Greta Generati ◽  
Eleonora Alfonzetti ◽  
...  
Keyword(s):  
Heart Disease ◽  
Right Ventricular ◽  
Pulmonary Circulation ◽  
Left Atrial ◽  
Left Ventricular ◽  
Left Ventricular Filling ◽  
Left Heart ◽  
Left Heart Disease ◽  
Ventricular Filling

scholarly journals Under pressure: pulmonary hypertension associated with left heart disease

2015 ◽  
Vol 24 (138) ◽  
pp. 665-673 ◽  
Author(s):  
Harrison W. Farber ◽  
Simon Gibbs
Keyword(s):  
Pulmonary Hypertension ◽  
Heart Disease ◽  
Survival Rates ◽  
Left Ventricular ◽  
Left Heart ◽  
Mean Pulmonary Arterial Pressure ◽  
Left Heart Disease ◽  
Right Heart Catheterisation ◽  
Pulmonary Capillary ◽  
Pulmonary Arterial

Pulmonary hypertension (PH) associated with left heart disease (PH-LHD) is the most common type of PH, but its natural history is not well understood. PH-LHD is diagnosed by right heart catheterisation with a mean pulmonary arterial pressure ≥25 mmHg and a pulmonary capillary wedge pressure >15 mmHg. The primary causes of PH-LHD are left ventricular dysfunction of systolic and diastolic origin, and valvular disease. Prognosis is poor and survival rates are low. Limited progress has been made towards specific therapies for PH-LHD, and management focuses on addressing the underlying cause of the disease with supportive therapies, surgery and pharmacological treatments. Clinical trials of therapies for pulmonary arterial hypertension in patients with PH-LHD have thus far been limited and have provided disappointing or conflicting results. Robust, long-term clinical studies in appropriate target populations have the potential to improve the outlook for patients with PH-LHD. Herein, we discuss the knowledge gaps in our understanding of PH-LHD, and describe the current unmet needs and challenges that are faced by clinicians when identifying and managing patients with this disease.

scholarly journals Echo-phonocardiographic determination of left atrial and left ventricular filling pressures with and without mitral stenosis.

Circulation ◽  
1980 ◽  
Vol 61 (5) ◽  
pp. 1043-1047 ◽  
Author(s):  
A R Palomo ◽  
M A Quinones ◽  
A D Waggoner ◽  
A G Kumpuris ◽  
R R Miller
Keyword(s):  
Mitral Stenosis ◽  
Left Atrial ◽  
Left Ventricular ◽  
Left Ventricular Filling ◽  
Ventricular Filling

scholarly journals The effect of Valsalva manouevre on left atrial and left ventricular filling in patients with hiatal hernia

2015 ◽  
Vol 24 ◽  
pp. S365
Author(s):  
C. Naoum ◽  
L. Kritharides ◽  
S. Gnanenthiran ◽  
D. Hanzek ◽  
Z. Pogrebizhsky ◽  
...  
Keyword(s):  
Hiatal Hernia ◽  
Left Atrial ◽  
Left Ventricular ◽  
Left Ventricular Filling ◽  
Ventricular Filling
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