Membranous proliferation of lens epithelial cells on acrylic, silicone, and poly(methyl methacrylate) lenses

2001 ◽  
Vol 27 (10) ◽  
pp. 1591-1595 ◽  
Author(s):  
Daijiro Kurosaka ◽  
Katsuhiko Kato
Keyword(s):  
Epithelial Cells ◽  
Methyl Methacrylate ◽  
Lens Epithelial Cells ◽  
Poly Methyl Methacrylate

Platelet Microtubule Subunit Proteins

1979 ◽  
Vol 42 (05) ◽  
pp. 1630-1633 ◽  
Author(s):  
A G Castle ◽  
N Crawford
Keyword(s):  
Epithelial Cells ◽  
Gel Electrophoresis ◽  
Blood Platelets ◽  
Polyacrylamide Gel Electrophoresis ◽  
Polyacrylamide Gel ◽  
Lens Epithelial Cells ◽  
Molecular Weights ◽  
Kinetics Of ◽  
Microtubular Structures

SummaryBlood platelets contain microtubule proteins (tubulin and HMWs) which can be polymerised “in vitro” to form structures which resemble the microtubules seen in the intact platelet. Platelet tubulin is composed of two non-identical subunits a and p tubulin which have molecular weights around 55,000 but can be resolved in alkaline SDS-polyacrylamide gel electrophoresis. These subunits associate as dimers with sedimentation coefficients of about 5.7 S although it is not known whether the dimer protein is a homo- or hetero-dimer. The dimer tubulin binds the anti-mitotic drug colchicine and the kinetics of this binding are similar to those reported for neurotubulins. Platelet microtubules also contain two HMW proteins which appear to be essential and integral components of the fully assembled microtubule. These proteins have molecular weights greater than 200,000 daltons. Fluorescent labelled antibodies to platelet and brain tubulins stain long filamentous microtubular structures in bovine lens epithelial cells and this pattern of staining is prevented by exposing the cells to conditions known to cause depolymerisation of cell microtubules.

Phototoxicity in Human Lens Epithelial Cells Promoted by St. John's Wort¶

2004 ◽  
Vol 80 (3) ◽  
pp. 583 ◽  
Author(s):  
Yu-Ying He ◽  
Colin F. Chignell ◽  
David S. Miller ◽  
Usha P. Andley ◽  
Joan E. Roberts
Keyword(s):  
Epithelial Cells ◽  
Human Lens ◽  
Lens Epithelial Cells ◽  
St John’S Wort ◽  
Human Lens Epithelial Cells ◽  
St John's Wort
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