Expression of protein gene product 9.5 in the anterior lens epithelial cells of atopic cataracts

2002 ◽  
Vol 28 (11) ◽  
pp. 2035-2039 ◽  
Author(s):  
Junko Nakajima ◽  
Atsushi Mekada ◽  
Jiro Nakamura ◽  
Yasuhiro Nishida ◽  
Yoshimitsu Tokunaga
Keyword(s):  
Epithelial Cells ◽  
Gene Product ◽  
Protein Gene ◽  
Lens Epithelial Cells ◽  
Protein Gene Product 9.5 ◽  
Protein Gene Product

scholarly journals Protein gene product 9.5 and ubiquitin are expressed in metabolically active epithelial cells of normal and pathologic human kidney

2005 ◽  
Vol 20 (12) ◽  
pp. 2714-2719 ◽  
Author(s):  
Francesca Diomedi-Camassei ◽  
Lucilla Ravà ◽  
Evelyne Lerut ◽  
Francesco Callea ◽  
Boudewijn Van Damme
Keyword(s):  
Epithelial Cells ◽  
Gene Product ◽  
Protein Gene ◽  
Human Kidney ◽  
Protein Gene Product 9.5 ◽  
Protein Gene Product

scholarly journals Protein Gene Product 9.5 Is Selectively Localized in Parietal Epithelial Cells of Bowman's Capsule in the Rat Kidney

2000 ◽  
Vol 11 (12) ◽  
pp. 2381-2386
Author(s):  
ISAO SHIRATO ◽  
KATSUHIKO ASANUMA ◽  
YUKIHIKO TAKEDA ◽  
KAYO HAYASHI ◽  
YASUHIKO TOMINO
Keyword(s):  
Epithelial Cells ◽  
Gene Product ◽  
Protein Gene ◽  
Rat Kidney ◽  
Protein Gene Product 9.5 ◽  
Pgp 9.5 ◽  
Shaped Body ◽  
Protein Gene Product ◽  
Selective Localization ◽  
Parietal Epithelial Cells

Abstract. Parietal epithelial cells (PEC) of Bowman's capsules cover the inner aspect of Bowman's capsules and are believed to contribute to extracapillary lesions of glomerulonephritis such as crescent formation. In glomerular research including cell culture experiments and pathology, differentiation between PEC and podocytes has frequently been a major problem. Immunohistochemistry of the adult rat kidney for protein gene product 9.5 (PGP 9.5), a neuron-specific ubiquitin C-terminal hydrolase, demonstrated selective localization of the immunoreactivity in PEC. At the urinary pole of the glomerulus, immunoreactive PEC were clearly differentiated from proximal tubular cells that were negative for PGP 9.5. In the subcapsular nephrogenic zone of newborn rat kidney, immunoreactivity was observed in almost all cells in the commashaped body and early S-shaped body and selectively in PEC in the late S-shaped body and capillary-stage glomerulus. In rat glomerular disease models (Masugi-nephritis and puromycin aminonucleoside nephrosis), cells that consisted of cellular crescents or adhered to glomerular tufts were positive for PGP 9.5. The selective localization of PGP 9.5 in PEC in rat kidney provides a new cytochemical marker for identifying the cells. Development expression of the protein suggests that PGP 9.5 is involved in the processes of nephrogenesis of rat kidney.

Ultrastructural localization and regulation of protein gene product 9.5

Neuroreport ◽  
1997 ◽  
Vol 8 (14) ◽  
pp. 2999-3004 ◽  
Author(s):  
Whei-Min Lin ◽  
Sung-Tsang Hsieh ◽  
Ia-Tang Huang ◽  
John W. Griffin ◽  
Wen-Pin Chen
Keyword(s):  
Gene Product ◽  
Protein Gene ◽  
Ultrastructural Localization ◽  
Protein Gene Product 9.5 ◽  
Protein Gene Product
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