Persistent mania and psychosis in a case of novel influenza a (H1N1) virus encephalitis

2011 ◽  
Vol 26 (S2) ◽  
pp. 406-406 ◽  
Author(s):  
J.Y. Teng ◽  
T.-S. Lee
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
Antiviral Treatment ◽  
Acute Infection ◽  
Psychotic Symptoms ◽  
Reye Syndrome ◽  
H1n1 Infection ◽  
Sequence Of Events ◽  
Influenza A H1n1 ◽  
Novel Influenza A

Neurologic complications associated with novel influenza A (H1N1) virus infection include seizures, encephalitis, encephalopathy and Reye syndrome. Mania and psychotic episodes are less commonly described, and there have been limited studies on the long-term neuropsychiatric sequelae of H1N1 infection.Here, we report a case of H1N1 infection with concurrent onset of acute manic and psychotic symptoms. Despite completing a full course of the antiviral medication oseltamivir, the patient's behaviour worsened over the next four weeks and he required readmission for psychiatric treatment. Based on the temporal sequence of events, we considered the possibility that these symptoms were sequelae of Novel influenza A (H1N1) infection. Moreover, the manic symptoms persisted weeks after the acute infection had abated, which gives rise to the consideration of long-lasting direct or indirect neuronal insult by the influenza virus. However, it is also possible that his symptoms may have represented a primary psychiatric disorder precipitated by or coincident with the viral infection.After treatment with antipsychotic medication and a mood stabiliser, his manic and psychotic symptoms became significantly attenuated. His behaviour improved considerably such that he was able to return to school. Medications were stopped after one month of outpatient follow-up at his behest. Four months after discharge, he was completely free of symptoms and was performing well in school.Treatment of influenza with antiviral medications has been shown to reduce the rate of complications. However, the effectiveness of antiviral treatment to prevent influenza-associated neuropsychiatric sequelae is unknown.

scholarly journals EPIDEMIOLOGI DAN DIAGNOSIS KEDOKTERAN LABORATORIK INFEKSI VIRUS H1N1

2018 ◽  
Vol 16 (3) ◽  
pp. 140
Author(s):  
J Sembiring ◽  
O Sianipar
Keyword(s):  
Sore Throat ◽  
Influenza A ◽  
Clinical Symptoms ◽  
H1n1 Virus ◽  
Antiviral Treatment ◽  
H1n1 Infection ◽  
Rt Pcr ◽  
Virus Family ◽  
Infection Diagnosis ◽  
Influenza A H1n1

H1N1 virus is an influenza virus family orthomyxoviridae, which clinical symptoms consist of: fever, cough, sore throat and headache. The virus can spread from person to person through airborne droplets and so a good infection control in the community or in healthworkers is needed, for instance by washing hands properly and PPE (Personal Protective Equipment). In October 4, 2009 there were over375.000 reported cases in which 4500 people were died. On June 11, 2009 the WHO stairs announced that H1N1 is the first pandemicin the 21st century. (The Indonesia people province was infecting by H1N1with 20 deaths until August 5, 2009). The purpose of thisarticle is to find out the epidemiological aspects as well as the diagnosis of influenza A H1N1 virus. From the website was found about1.110.000 sources, and after downloading them are selected as they are written only in the bibliography. From the searched informationobtained, it was known that H1N1 infection diagnosis begins with the discovery of heat (temperature ≥ 100° F [37.8° C]) and cough or sore throat. No cause other than influenza that is called with ILI was found. The informed laboratory examination is divided into three parts are confirmed if ILI was found as well as the virus in the throat or nasal swab by RT-PCR and/or virus culture; probably the ILIhas positive results of influenza A RT-PCR, but if the results are negative including the laboratorial findings, the basis of epidemiologyin this case was only suspected. Laboratory plays an important role in the establishing of the H1N1 infection diagnosis Rapid diagnosisis important to reduce infection, to protect patients from complications by antiviral treatment in the right time and also to provideimmediate information for the public.

Clinical Features of Hospitalized Adult Patients with Pneumonia in Novel Influenza A (H1N1) Infection

2010 ◽  
Vol 69 (1) ◽  
pp. 24 ◽  
Author(s):  
Chang Hoon Han ◽  
Yu Kyung Hyun ◽  
Yu Ri Choi ◽  
Na Young Sung ◽  
Yoon Seon Park ◽  
...  
Keyword(s):  
Clinical Features ◽  
Influenza A ◽  
Adult Patients ◽  
H1n1 Infection ◽  
Influenza A H1n1 ◽  
Novel Influenza A

scholarly journals The mutation network for the hemagglutinin gene from the novel influenza A (H1N1) virus

2009 ◽  
Vol 54 (13) ◽  
pp. 2168-2170 ◽  
Author(s):  
YunGang He ◽  
GuoHui Ding ◽  
Chao Bian ◽  
Zhong Huang ◽  
Ke Lan ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
The Novel ◽  
Influenza A H1n1 ◽  
Hemagglutinin Gene ◽  
Novel Influenza A

PERICARDIAL EFFUSION COMPLICATING NOVEL INFLUENZA A (H1N1) INFECTION IN AN INFANT

2010 ◽  
Vol 29 (8) ◽  
pp. 782-783 ◽  
Author(s):  
Katalin Koranyi ◽  
Dustin Yontz ◽  
Zachary Rohrer ◽  
Amy Leber ◽  
Octavio Ramilo
Keyword(s):  
Pericardial Effusion ◽  
Influenza A ◽  
H1n1 Infection ◽  
Influenza A H1n1 ◽  
Novel Influenza A

Detection of novel influenza A(H1N1) virus by real-time RT-PCR

2009 ◽  
Vol 45 (3) ◽  
pp. 203-204 ◽  
Author(s):  
David M. Whiley ◽  
Seweryn Bialasiewicz ◽  
Cheryl Bletchly ◽  
Cassandra E. Faux ◽  
Bruce Harrower ◽  
...  
Keyword(s):  
Real Time ◽  
Influenza A ◽  
H1n1 Virus ◽  
Rt Pcr ◽  
Influenza A H1n1 ◽  
Novel Influenza A

scholarly journals The novel influenza a (H1N1) infection in infants and children

1970 ◽  
Vol 8 (4) ◽  
pp. 84-90
Author(s):  
Musa Mohd. Nordin
Keyword(s):  
Influenza A ◽  
Infants And Children ◽  
The Novel ◽  
H1n1 Infection ◽  
Medical Sciences ◽  
Influenza A H1n1 ◽  
Spanish Flu ◽  
Novel Influenza A ◽  
In Infants And Children

During the 1918 Spanish Flu pandemic, often described as the most devastating epidemic in recorded history, 1 in 5 person was infected and an estimated 50 million lives were lost. The disease was so widespread and pervasive that even the children had a tune which they skipped rope to: I had a little bird, its name was Enza, I opened the window and In-Flu-Enza. DOI: 10.3329/bjms.v8i4.4705 Bangladesh Journal of Medical Sciences Vol.8(4); October 2009 pp84-90

scholarly journals Hospitalized Adult Patients with 2009 Pandemic Influenza A (H1N1) in Kaunas, Lithuania

Medicina ◽  
2011 ◽  
Vol 47 (1) ◽  
pp. 11-18 ◽  
Author(s):  
◽  
◽  
◽  
◽  
◽  
...  
Keyword(s):  
Risk Factors ◽  
Symptom Onset ◽  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
Clinical Course ◽  
Antiviral Treatment ◽  
Course Of Illness ◽  
Influenza A H1n1 ◽  
Complicated Course

The objective of this study was to identify case characteristics and clinical course of the disease in patients hospitalized with 2009 pandemic influenza A (H1N1) infection during the first wave of the pandemic and to identify risk factors associated with the complicated course of illness. Material and methods. A retrospective study of adult cases of the laboratory-confirmed 2009 pandemic influenza A (H1N1) virus admitted to three hospitals in Kaunas between November 1, 2009, and March 15, 2010, was carried out. The main outcome measures were clinical characteristics, risk factors for complicated disease, treatment, and clinical course of the disease. Results. The study enrolled 121 of the 125 patients hospitalized due to 2009 pandemic influenza A (H1N1) virus infection. The median age was 31 years (range, 18–83); 5% of the patients were aged more than 65 years. Pregnant and postpartum women comprised 26% of all hospitalized cases. Nearly half (49.5%) of those who underwent chest radiography had findings consistent with pneumonia, which was bilateral in one-third of cases. The risk to have pandemic influenza complicated by pneumonia increased significantly with one-day delay from symptom onset to antiviral treatment (OR, 2.241; 95% CI, 1.354–3.710). More than half (57%) of the patients received antiviral treatment. In 45% of the treated patients, antiviral drugs were administered within 48 hours from symptom onset. Intensive care was required in 7.4% of the cases. The overall mortality was 5% (6/121). The median age of the patients who died was 43.5 years (range, 23–62); 4 patients had been previously healthy, 1 patient suffered from chronic lympholeukemia, and 1 patient was a pregnant woman. Conclusion. The 2009 pandemic influenza A (H1N1) caused considerable morbidity in a significant proportion of hospitalized adults. The main risk factor associated with the complicated course of illness was delayed antiviral treatment.

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