Influence of counterions on antimicrobial activity of quaternary ammonium salts

1996 ◽  
Vol 4 ◽  
pp. S191 ◽  
Author(s):  
D. Mynacik ◽  
F. Devinsky ◽  
I. Lacko
Pathogens ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 459 ◽  
Author(s):  
Dobrawa Kwaśniewska ◽  
Ying-Lien Chen ◽  
Daria Wieczorek

Besides their positive role, microorganisms are related to a number of undesirable effects, including many diseases, biodeterioration and food spoilage, so when their presence is undesired, they must be controlled. Numerous biocides limiting the development of microorganisms have been proposed, however, in this paper the biocidal and inhibitory activity of quaternary ammonium salts (QASs) and their zwitterionic derivatives is addressed. This paper presents the current state of knowledge about the biocidal activity of QAS and their derivatives. Moreover, the known mechanisms of antimicrobial activity and the problem of emerging resistance to QAS are discussed. The latest trends in the study of surfactants and their potential use are also presented.


1979 ◽  
Vol 34 (5-6) ◽  
pp. 485-486 ◽  
Author(s):  
Ivan Lacko ◽  
Ferdinand Devínsky ◽  
Ľudovít Krasnec ◽  
Dušan Mlynarčik

Abstract N,N-Dialkyl Ammonium Salts of Saturated Heterocyclic Amines, Antimicrobial Activity Antimicrobial activity of N-alkyl-N-dodecylpiperidinium bromides and N-ethyl-N-dodecylheterocycloalkyl ammonium bromides (pyrrolidine, morpholine, perhydroazepine) deter­ mined on grampositive and gramnegative bacteria, yeasts and moulds, presented as minimum inhibition concentration (MIC). Comparison of the effect of change of structure: lenghtening of alkyl chain, change of heterocyclic ring. Change in the lenght of alkyl chain markedly affects the antimicrobial activity, change of heterocyclic ring has no substantial effect. The most active compounds were N-heptyl-and N-hexyl-N-dodecylpiperidinium bromides.


ChemInform ◽  
2010 ◽  
Vol 22 (31) ◽  
pp. no-no
Author(s):  
C. V. R. SASTRY ◽  
O. P. BANSAL ◽  
B. LAL ◽  
S. C. CHATURVEDI ◽  
J. S. SRINIVAS ◽  
...  

Il Farmaco ◽  
1998 ◽  
Vol 53 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Fridrich Gregan ◽  
Jarmila Oremusová ◽  
Milan Remko ◽  
Juraj Gregan ◽  
Dušan Mlynarčík

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