Synthesis and Biological activity of kappa opioid receptor agonists. Part 2: Preparation of 3-aryl-2-pyridone analogues generated by solution- and solid-phase parallel synthesis methods

2003 ◽  
Vol 13 (6) ◽  
pp. 1141-1145 ◽  
Author(s):  
Graeme Semple ◽  
Britt-Marie Andersson ◽  
Vijay Chhajlani ◽  
Jennie Georgsson ◽  
Magnus J Johansson ◽  
...  
Keyword(s):  
Biological Activity ◽  
Opioid Receptor ◽  
Solid Phase ◽  
Kappa Opioid Receptor ◽  
Parallel Synthesis ◽  
Synthesis Methods ◽  
Kappa Opioid ◽  
Receptor Agonists ◽  
Opioid Receptor Agonists

scholarly journals Cover Feature: Synthesis and Assessment of Fused β‐Carboline Derivatives as Kappa Opioid Receptor Agonists (12/2021)

ChemMedChem ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. 1834-1834
Author(s):  
Veena D. Yadav ◽  
Lalan Kumar ◽  
Poonam Kumari ◽  
Sakesh Kumar ◽  
Maninder Singh ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Kappa Opioid Receptor ◽  
Kappa Opioid ◽  
Receptor Agonists ◽  
Opioid Receptor Agonists

EVIDENCE FOR A CENTRAL OPIOID CONTROL OF RUMINATION

1984 ◽  
Vol 64 (5) ◽  
pp. 13-15 ◽  
Author(s):  
Y. RUCKEBUSCH ◽  
TH. BARDON
Keyword(s):  
Key Words ◽  
Opioid Receptor ◽  
Opioid Receptors ◽  
Opioid Peptides ◽  
Kappa Opioid Receptor ◽  
Kappa Opioid ◽  
Receptor Agonists ◽  
Opioid Agonists ◽  
Reflex Control ◽  
Opioid Receptor Agonists

Intravenous adrenaline induced reticular extracontractions and rumination within 26 sec in hay-fed, and 184 sec in cube-fed sheep. Regardless of diet, pretreatment with cerebroventricular infusion of kappa-opioid-receptor agonists enhanced this reflex. Control of rumination may involve multiple opioid-receptors, since inhibition of the reflex occurred after mu- and delta-opioid-agonists. Key words: Sheep, rumination, opioid-peptides

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