The role of dopamine transporter imaging agent [ 99m Tc]TRODAT-1 in hemi-parkinsonism rat brain

2001 ◽  
Vol 28 (8) ◽  
pp. 923-928 ◽  
Author(s):  
Yen-Kung Chen ◽  
Ren-Shyan Liu ◽  
Wen-Sheng Huang ◽  
Shiaw-Pyng Wey ◽  
Gann Ting ◽  
...  
Keyword(s):  
Rat Brain ◽  
Dopamine Transporter ◽  
Imaging Agent ◽  
Dopamine Transporter Imaging

[99mTc]TRODAT-1: A novel technetium-99m complex as a dopamine transporter imaging agent

1997 ◽  
Vol 24 (4) ◽  
pp. 372-380 ◽  
Author(s):  
Mei-Ping Kung ◽  
D. Andrew Stevenson ◽  
Karl Pl�ssl ◽  
Sanath K. Meegalla ◽  
Andrew Beckwith ◽  
...  
Keyword(s):  
Dopamine Transporter ◽  
Imaging Agent ◽  
Dopamine Transporter Imaging ◽  
Technetium 99M

[ 99m Tc]TRODAT-1: a novel technetium-99m complex as a dopamine transporter imaging agent

1997 ◽  
Vol 24 (4) ◽  
pp. 372-380 ◽  
Author(s):  
Mei-Ping Kung ◽  
D. Andrew Stevenson ◽  
Karl Plössl ◽  
Sanath K. Meegalla ◽  
Andrew Beckwith ◽  
...  
Keyword(s):  
Dopamine Transporter ◽  
Imaging Agent ◽  
Dopamine Transporter Imaging ◽  
Technetium 99M

Role of dopamine transporter imaging in the diagnosis of atypical tremor disorders

2003 ◽  
Vol 18 (S7) ◽  
pp. S22-S27 ◽  
Author(s):  
Vicky Marshall ◽  
Donald G. Grosset
Keyword(s):  
Dopamine Transporter ◽  
Dopamine Transporter Imaging

Dementia with Lewy bodies versus Alzheimer's disease: Role of dopamine transporter imaging

2003 ◽  
Vol 18 (S7) ◽  
pp. S34-S38 ◽  
Author(s):  
Durval C. Costa ◽  
Zuzana Walker ◽  
Rodney W.H. Walker ◽  
Fl�via R.G. Fontes
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Dopamine Transporter ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies ◽  
Dopamine Transporter Imaging

scholarly journals Dopamine Transporter Imaging, Current Status of a Potential Biomarker: A Comprehensive Review

2021 ◽  
Vol 22 (20) ◽  
pp. 11234
Author(s):  
Giovanni Palermo ◽  
Sara Giannoni ◽  
Gabriele Bellini ◽  
Gabriele Siciliano ◽  
Roberto Ceravolo
Keyword(s):  
Dopamine Transporter ◽  
Predictive Biomarker ◽  
Current Status ◽  
Imaging Biomarker ◽  
Target Engagement ◽  
Major Goal ◽  
Dopamine Transporter Imaging ◽  
Potential Biomarker ◽  
The Status

A major goal of current clinical research in Parkinson’s disease (PD) is the validation and standardization of biomarkers enabling early diagnosis, predicting outcomes, understanding PD pathophysiology, and demonstrating target engagement in clinical trials. Molecular imaging with specific dopamine-related tracers offers a practical indirect imaging biomarker of PD, serving as a powerful tool to assess the status of presynaptic nigrostriatal terminals. In this review we provide an update on the dopamine transporter (DAT) imaging in PD and translate recent findings to potentially valuable clinical practice applications. The role of DAT imaging as diagnostic, preclinical and predictive biomarker is discussed, especially in view of recent evidence questioning the incontrovertible correlation between striatal DAT binding and nigral cell or axon counts.

First Example of a 99mTc Complex as a Dopamine Transporter Imaging Agent

1995 ◽  
Vol 117 (44) ◽  
pp. 11037-11038 ◽  
Author(s):  
Sanath Meegalla ◽  
Karl Ploessl ◽  
Mei-Ping Kung ◽  
D. Andrew Stevenson ◽  
Louise M. Liable-Sands ◽  
...  
Keyword(s):  
Dopamine Transporter ◽  
Imaging Agent ◽  
Dopamine Transporter Imaging ◽  
99Mtc Complex

The preclinical pharmacologic study of dopamine transporter imaging agent [99mTc]TRODAT-1

2000 ◽  
Vol 27 (1) ◽  
pp. 69-75 ◽  
Author(s):  
Ping Fang ◽  
Chun-ying Wu ◽  
Zhen-guo Liu ◽  
Wei-xing Wan ◽  
Tie-sheng Wang ◽  
...  
Keyword(s):  
Dopamine Transporter ◽  
Imaging Agent ◽  
Dopamine Transporter Imaging ◽  
Pharmacologic Study
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