Upper Airway Surgery Benefits Patients With Obstructive Sleep Apnoea Who Cannot Tolerate Nasal Continuous Positive Airway Pressure

2006 ◽  
Vol 2006 ◽  
pp. 143-144
Author(s):  
M.A. Keefe
Keyword(s):  
Continuous Positive Airway Pressure ◽  
Obstructive Sleep Apnoea ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Upper Airway ◽  
Sleep Apnoea ◽  
Upper Airway Surgery ◽  
Airway Surgery ◽  
Obstructive Sleep

Upper airway surgery benefits patients with obstructive sleep apnoea who cannot tolerate nasal continuous positive airway pressure

2004 ◽  
Vol 118 (4) ◽  
pp. 270-274 ◽  
Author(s):  
Melanie A. Souter ◽  
Scott Stevenson ◽  
Bryn Sparks ◽  
Chris Drennan
Keyword(s):  
Continuous Positive Airway Pressure ◽  
Obstructive Sleep Apnoea ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Upper Airway ◽  
Sleep Apnoea ◽  
Upper Airway Surgery ◽  
Nasal Cpap ◽  
Airway Surgery ◽  
Obstructive Sleep

Nasal continuous positive airway pressure (CPAP) is the mainstay of treatment for patients with moderate to severe obstructive sleep apnoea (OSA). However, tolerance and compliance are poor.An audit using the Christchurch Hospital ORL surgery database identified patients who underwent upper airway surgery for OSA. Tracheostomy and bimaxillary advancement patients were excluded. Adults with moderate to severe OSA (Desaturation Index (DI) >10 n.h-1), who had failed atrial of nasal CPAP, and had pre-operative and post-operative sleep study data were identified. Objective (DI) and Subjective (Epworth Sleepiness Score (ESS)) outcome measures were recorded.The database identified 69 patients who underwent surgery for snoring or OSA; of these, 25 patients formed the study group. Sixteen out of 25 improved (64 per cent) after surgery, seven out of 25 showed no change (28 per cent), two patients (eight per cent) showed deterioration in their DI. Forty-eight per cent of patients had >50 per cent post-operative improvement in DI. Fourteen out of 25 (56 per cent) had a post-operative DI <20 n.h-1. Seven out of 25 (28 per cent) had a post-operative DI <10 n.h-1. Upper airway surgery has a role in the managementof selected patients with OSA who cannot tolerate nasal CPAP.

A case of severe obstructive sleep apnoea in Madelung's disease treated by lateral pharyngoplasty

2017 ◽  
Vol 131 (9) ◽  
pp. 834-837 ◽  
Author(s):  
V Pinto ◽  
P G Morselli ◽  
D Tassone ◽  
O Piccin
Keyword(s):  
Continuous Positive Airway Pressure ◽  
Obstructive Sleep Apnoea ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Upper Airway ◽  
Sleep Apnoea ◽  
Pressure Therapy ◽  
Madelung's Disease ◽  
Madelung’S Disease ◽  
Obstructive Sleep

AbstractBackground:Madelung's disease is a rare disorder characterised by the presence of multiple, symmetric, non-capsulated fat masses in the face, neck and other areas of upper extremities. In some cases, severe clinical complications such as upper airway compression can occur.Case report:A 56-year-old man affected by Madelung's disease complained of snoring and severe daytime sleepiness. Polysomnography revealed severe obstructive sleep apnoea. An attempt to treat sleep apnoea by continuous positive airway pressure failed because of poor compliance. Functional expansion pharyngoplasty was carried out as an initial treatment. Marked improvement of neck movements and normalisation of somnographic parameters were observed at six months’ follow up.Conclusion:Patients with Madelung's disease should be examined carefully for potential obstructive sleep apnoea. Although continuous positive airway pressure remains the treatment of choice, specific surgery can be used in those patients who cannot tolerate continuous positive airway pressure therapy.

scholarly journals Continuous Positive Airway Pressure Treatment: Effect on Serum Lipids in Patients with Obstructive Sleep Apnoea

2011 ◽  
Vol 5 (1) ◽  
pp. 231-238 ◽  
Author(s):  
Vassileios Michailidis ◽  
Paschalis Steiropoulos ◽  
Evangelia Nena ◽  
Nikolaos Papanas ◽  
Efstratios Maltezos ◽  
...  
Keyword(s):  
Continuous Positive Airway Pressure ◽  
Beneficial Effect ◽  
Obstructive Sleep Apnoea ◽  
Airway Pressure ◽  
Serum Lipids ◽  
Positive Airway Pressure ◽  
Density Lipoprotein ◽  
Upper Airway ◽  
Sleep Apnoea ◽  
Obstructive Sleep

Obstructive Sleep Apnoea (OSA) is a common disorder in adults. Its hallmark is repetitive episodes of partial or complete obstruction of the upper airway during sleep associated with increasing respiratory efforts. This leads to oxyhaemoglobin desaturation, sleep fragmentation, and daytime symptoms, mainly excessive sleepiness. Accumulating evidence suggests that intermittent hypoxia and oxyhaemoglobin desaturation may, irrespective of obesity, lead to elevation of serum lipids even in non-dyslipidaemic OSA patients. Continuous Positive Airway Pressure (CPAP) is the treatment of choice for OSA, since it eliminates upper airway collapse during sleep and improves sleep fragmentation, daytime symptoms and quality of life. Moreover, it has been proposed that the amelioration of breathing disturbances during sleep can improve several markers of the lipid profile, such as total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol as well as apolipoproteins A, B and C. Indeed, some studies have reported improvements in these parameters especially in CPAP adherent patients. However, other studies failed to confirm this beneficial effect. The present article reviews the issue whether CPAP treatment exerts a beneficial effect on lipids.

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