External ion accumulation of low molecular weight poly(ethylene glycol) by electrospray ionization fourier transform mass spectrometry

1999 ◽  
Vol 10 (12) ◽  
pp. 1298-1304 ◽  
Author(s):  
E. Peter Maziarz ◽  
Gary A. Baker ◽  
Sarah A. Lorenz ◽  
Troy D. Wood
Keyword(s):  
Mass Spectrometry ◽  
Molecular Weight ◽  
Fourier Transform ◽  
Ethylene Glycol ◽  
Electrospray Ionization ◽  
Fourier Transform Mass Spectrometry ◽  
Low Molecular Weight ◽  
Poly Ethylene Glycol ◽  
Electrospray Ionization Fourier Transform ◽  
Poly Ethylene

scholarly journals Advantages of Molecular Weight Identification during Native MS Screening

Planta Medica ◽  
2018 ◽  
Vol 84 (16) ◽  
pp. 1201-1212
Author(s):  
Ahad Khan ◽  
Anne Bresnick ◽  
Sean Cahill ◽  
Mark Girvin ◽  
Steve Almo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Molecular Weight ◽  
Fourier Transform ◽  
T Cell ◽  
Electrospray Ionization ◽  
Fourier Transform Mass Spectrometry ◽  
Protein Complexes ◽  
Native Mass Spectrometry ◽  
Biochanin A ◽  
Electrospray Ionization Fourier Transform

AbstractNative mass spectrometry detection of ligand-protein complexes allowed rapid detection of natural product binders of apo and calcium-bound S100A4 (a member of the metal binding protein S100 family), T cell/transmembrane, immunoglobulin (Ig), and mucin protein 3, and T cell immunoreceptor with Ig and ITIM (immunoreceptor tyrosine-based inhibitory motif) domains precursor protein from extracts and fractions. Based on molecular weight common hits were detected binding to all four proteins. Seven common hits were identified as apigenin 6-C-β-D-glucoside 8-C-α-L-arabinoside, sweroside, 4′,5-dihydroxy-7-methoxyflavanone-6-C-rutinoside, loganin acid, 6-C-glucosylnaringenin, biochanin A 7-O-rutinoside and quercetin 3-O-rutinoside. Mass guided isolation and NMR identification of hits confirmed the mass accuracy of the ligand in the ligand-protein MS complexes. Thus, molecular weight ID from ligand-protein complexes by electrospray ionization Fourier transform mass spectrometry allowed rapid dereplication. Native mass spectrometry using electrospray ionization Fourier transform mass spectrometry is a tool for dereplication and metabolomics analysis.

Microporous Bio-Membrane Materials Based on High Molecular Weight Polylactide and Low Molecular Weight Poly(ethylene glycol)

2012 ◽  
Vol 567 ◽  
pp. 123-126
Author(s):  
Teng Fei Shen ◽  
Man Geng Lu ◽  
Li Yan Liang
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
High Weight ◽  
Low Molecular Weight ◽  
Poly Ethylene Glycol ◽  
Degradation Rates ◽  
Degradation Behaviors ◽  
The Mean ◽  
Poly Ethylene ◽  
Lower Glass Transition Temperature

In this work, microporous membrane biomaterials based on high weight molecular polylactide (PLA) and low molecular weight poly(ethylene glycol) (PEG) using rapid solvent evaporation method were prepared and investigated. The effect of PEG segments added on the thermal and degradation behaviors was studied. According to the results, produced PLA/PEG biomaterial has lower glass transition temperature (Tg)in comparison with neat PLA. It was also found that the degradation rates of the PLA/PEG biomaterials were significantly increased with adding of PEG, which explained by increasing hydrophilic groups. For better porous fixation, CL-blocked polyisocyanate (CL-bp), which was synthesized from reaction of isophorone diisocyanate (IPDI) with dimethylol propionic acid (DMPA) and Trimethylolpropane (TMP) followed by addition of caprolactam (CL), were introduced. The microporous forms were observed by the scanning electron microscope (SEM), which showed the mean diameters of prepared PLA/PEG microporous were around 10μm.

Plasticization of poly(lactide) with blends of tributyl citrate and low molecular weight poly(d,l-lactide)-b-poly(ethylene glycol) copolymers

2009 ◽  
Vol 45 (10) ◽  
pp. 2839-2848 ◽  
Author(s):  
Yahia Lemmouchi ◽  
Marius Murariu ◽  
Ana Margarida Dos Santos ◽  
Allan J. Amass ◽  
Etienne Schacht ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
Low Molecular Weight ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
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