The paper deals with problem analysis due to domestic engineering transition to the Industry 4.0 technology. It presents such innovative technologies as additive manufacturing (3D-printing), Industrial Internet of Things, total digitization of manufacturing (digital description of products and processes, virtual and augmented reality). Among the main highlighted problems the authors include a lack of unification and standardization at this stage of technology development; incompleteness of both domestic and international regulatory framework; shortage of qualified personnel.