828 cKIT expression in adult primitive neuroectodermal tumor (PNET) and Ewing's sarcoma: a retrospective immunohistochemical study

2003 ◽  
Vol 1 (5) ◽  
pp. S249
Author(s):  
I.O. Kara ◽  
S. Erdogan ◽  
B. Sahin ◽  
M. Ergin ◽  
G. Gönlüsen ◽  
...  
1998 ◽  
Vol 1 (2) ◽  
pp. 125-130 ◽  
Author(s):  
E.J. Lazda ◽  
P.J. Berry

Bone marrow metastases from small round cell tumors can present diagnostic difficulties. In this study, we assessed the value of immunohistochemistry, using two monoclonal antibodies to CD99, for the diagnosis of metastatic disease in bone marrow trephine specimens from patients with Ewing's sarcoma or primitive neuroectodermal tumor (PNET). The proportions of specimens showing metastases were 10.3% with routine staining and 20.7% with immunohistochemistry. The specimens that were negative on conventional light microscopy and positive with immunohistochemistry all showed other abnormalities. The results do not support the routine use of immunohistochemistry in specimens that are normal by conventional light microscopy, but indicate that useful information may be gained in cases where marrow histology is obscured by fibrosis, necrosis, or distortion artefact. Neither of the two antibodies tested was superior for this purpose.


2016 ◽  
Vol 97 (3) ◽  
pp. 365-368 ◽  
Author(s):  
Yinghui Ding ◽  
Zhenlin Huang ◽  
Yafei Ding ◽  
Zhankui Jia ◽  
Chaohui Gu ◽  
...  

Author(s):  
Izabela S. Alves ◽  
Luiz G. Berriel ◽  
Rafael T. Alves ◽  
Mateus O. Potratz ◽  
Marcele B. Pinto ◽  
...  

2007 ◽  
Vol 22 (Suppl) ◽  
pp. S159 ◽  
Author(s):  
Yoon Young Lee ◽  
Do Hoon Kim ◽  
Ji Hye Lee ◽  
Jong Sang Choi ◽  
Kwang Ho In ◽  
...  

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