550 ORAL Population based mammography screening results in substantial savings in treatment costs by reducing the number of breast cancer deaths

2005 ◽  
Vol 3 (2) ◽  
pp. 153
2006 ◽  
Vol 98 (2) ◽  
pp. 143-150 ◽  
Author(s):  
Lea Kauhava ◽  
Pirjo Immonen-Räihä ◽  
Ilmo Parvinen ◽  
Kaija Holli ◽  
Pauliina Kronqvist ◽  
...  

Cancer ◽  
2021 ◽  
Author(s):  
Megan E. Tesch ◽  
Caroline Speers ◽  
Rekha M. Diocee ◽  
Lovedeep Gondara ◽  
Stuart J. Peacock ◽  
...  

1994 ◽  
Vol 1 (3) ◽  
pp. 184-187 ◽  
Author(s):  
Sven Törnberg ◽  
John Carstensen ◽  
Timo Hakulinen ◽  
Per Lenner ◽  
Thomas Hatschek ◽  
...  

To evaluate, by analysis of breast cancer mortality data from all the 26 Swedish counties for the years 1971 to 1990, whether the effect of the introduction of mammography screening in Sweden can be assessed by observation from existing mortality data. A Poisson regression model was used to study whether a decrease in breast cancer mortality among women aged 50–74 years was associated with the extent of mammography screening in different counties and periods. In regions where mammography screening had been introduced, breast cancer mortality tended to be decreased, on average, compared with regions with-'out screening. If a 10 year time lag between the start of screening and its full effect on mortality is assumed then the estimated reduction in breast cancer mortality associated with introduction of screening was 19% with a 95% confidence interval ranging from 3% to 37%. The results suggest that the effect of mammography screening may be studied using existing routine mortality data and appropriate statistical modelling. This way of assessing the outcome of the screening is valuable when continuously monitoring a screening programme that has become a public health routine.


The Breast ◽  
2003 ◽  
Vol 12 (5) ◽  
pp. 308-313 ◽  
Author(s):  
Pekka J Klemi ◽  
Ilmo Parvinen ◽  
Liisa Pylkkänen ◽  
Lea Kauhava ◽  
Pirjo Immonen-Räihä ◽  
...  

2014 ◽  
Vol 136 (6) ◽  
pp. 1411-1421 ◽  
Author(s):  
Kerri R. Beckmann ◽  
John W. Lynch ◽  
Janet E. Hiller ◽  
Gelareh Farshid ◽  
Nehmat Houssami ◽  
...  

2014 ◽  
Vol 136 (6) ◽  
Author(s):  
Deependra Singh ◽  
Nea Malila ◽  
Arun Pokhrel ◽  
Ahti Anttila

Author(s):  
Myrlene Jeudy ◽  
Monique Swain ◽  
Mark Pearlman

This widely discussed study by Bleyer and Welch published in The New England Journal of Medicine (NEJM) “The Effects of Three Decades of Screening Mammography on Breast Cancer Incidence” concluded that screening mammography leads to a substantial overdiagnosis of early breast cancer (estimated 69% increase) while only having a small effect on late-stage breast cancer (estimated 8% decrease). In a population-based observational study, the authors utilized trend data from the Surveillance, Epidemiology and End Results (SEER) database to examine trends on the incidence and stage of early- versus late-stage breast cancer at the time of diagnosis. They compared 2 time frames: prior to widespread mammography screening (1976–1978) and after mammography screening was introduced in the United States (2006––2008). This article reviews this NEJM article and describes several methodological assumptions by the authors that have been soundly criticized and the associated limitations. As a result of these limitations, there was an exaggeration of the overdiagnosis of early-stage disease with mammography and, more importantly, a substantial underestimate of the impact of mammography on decreasing late-stage breast cancer.


Author(s):  
Arnaud Seigneurin ◽  
Catherine Exbrayat ◽  
Florence Molinié ◽  
Lucie Croisier ◽  
Florence Poncet ◽  
...  

Abstract Meta-analyses of randomized controlled trials that started from 1963 to 1991 reported a decrease of breast cancer mortality associated with mammography screening. However, the effectiveness of population based screening programmes conducted nowadays may have changed, due to the better effectiveness of treatments for late stage cancers and the better diagnostic performance of mammography. The main objective of this study was to predict the reduction of breast cancer mortality associated with mammography screening in the French current setting. We compared breast cancer mortality in 2 simulated cohorts of women, which differed from each other solely by a 70% biennial participation in screening from 50 to 74 years old. The micro-simulation model used for predictions was calibrated with incidence rates of breast cancer by stage that were observed in Isère and Loire-Atlantique départements, France in 2007-2013. The model predicted a decrease of breast cancer mortality associated with mammography screening of 18% (95%CI: 5% - 31%) and 17% (95%CI: 3% - 29%), for models calibrated with data from Isère and Loire-Atlantique départements, respectively. Our results highlight the interest of biennial mammography screening from 50 to 74 years old to decrease breast cancer mortality in the current setting, despite improvement in treatment effectiveness.


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