PVIII-4 The role of human papillomavirus in non melanoma skin cancers

2009 ◽  
Vol 46 ◽  
pp. S43
Author(s):  
O. Keseroglu ◽  
N. Ilter ◽  
G. Bozdayi ◽  
S. Rota
Keyword(s):  
Human Papillomavirus ◽  
Skin Cancers ◽  
Melanoma Skin

scholarly journals A Case of Squamous Cell Carcinoma of Skin Subsequent to Subcutaneous Foreign Body

2016 ◽  
Vol 12 (1) ◽  
pp. 53-55
Author(s):  
P Anwar ◽  
S Mubashir ◽  
I Hassa ◽  
T Arif
Keyword(s):  
Squamous Cell Carcinoma ◽  
Foreign Body ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Foreign Bodies ◽  
Transposition Flap ◽  
Skin Cancers ◽  
Flap Closure ◽  
Melanoma Skin

Squamous cell carcinoma (SCC) of the skin is one of the most common non melanoma skin cancers (NMSC), along with basal cell carcinoma (BCC). Besides ultraviolet radiation, the role of exposure to industrial agents, ionizing radiation and areas of chronic inflammation is associated with the development of SCC. SCC may also be associated with foreign bodies. We report a rare case of cutaneous SCC in an elderly Kashmiri female, developing subsequent to subcutaneous non metallic foreign body, which was successfully excised with negative margins, and transposition flap closure. DOI: http://dx.doi.org/10.3126/njdvl.v12i1.10604 Nepal Journal of Dermatology, Venereology & Leprology Vol.12(1) 2014 pp.53-55

scholarly journals Detection of Human Papillomavirus DNA in PUVA-Associated Non-Melanoma Skin Cancers

1998 ◽  
Vol 111 (1) ◽  
pp. 123-127 ◽  
Author(s):  
Catherine A. Harwood ◽  
Patricia J. Spink ◽  
T. Surentheran ◽  
Irene M. Leigh ◽  
John L.M. Hawke ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Skin Cancers ◽  
Papillomavirus Dna ◽  
Melanoma Skin

The Role of Human Papillomaviruses in the Development of Non-Melanoma Skin Cancers

2013 ◽  
Vol 33 (4) ◽  
pp. 1112-1118
Author(s):  
Havva Özge KESEROĞLU ◽  
Nilsel İLTER ◽  
Saliha ROTA ◽  
Sühan AYHAN ◽  
Gülendam BOZDAYI ◽  
...  
Keyword(s):  
Human Papillomaviruses ◽  
Skin Cancers ◽  
Melanoma Skin

scholarly journals Human Papillomavirus and Cellular Pathways: Hits and Targets

Pathogens ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 262
Author(s):  
Alessandro Medda ◽  
Daria Duca ◽  
Susanna Chiocca
Keyword(s):  
Human Papillomavirus ◽  
Hpv Infection ◽  
Therapeutic Approaches ◽  
Complete Understanding ◽  
Cervical Cancers ◽  
Skin Cancers ◽  
Cellular Pathways ◽  
New Biomarkers ◽  
Vaccination Campaigns ◽  
Melanoma Skin

The Human Papillomavirus (HPV) is the causative agent of different kinds of tumors, including cervical cancers, non-melanoma skin cancers, anogenital cancers, and head and neck cancers. Despite the vaccination campaigns implemented over the last decades, we are far from eradicating HPV-driven malignancies. Moreover, the lack of targeted therapies to tackle HPV-related tumors exacerbates this problem. Biomarkers for early detection of the pathology and more tailored therapeutic approaches are needed, and a complete understanding of HPV-driven tumorigenesis is essential to reach this goal. In this review, we overview the molecular pathways implicated in HPV infection and carcinogenesis, emphasizing the potential targets for new therapeutic strategies as well as new biomarkers.

scholarly journals Behind the Scene: Exploiting MC1R in Skin Cancer Risk and Prevention

Genes ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 1093
Author(s):  
Michele Manganelli ◽  
Stefania Guida ◽  
Anna Ferretta ◽  
Giovanni Pellacani ◽  
Letizia Porcelli ◽  
...  
Keyword(s):  
Melanocortin 1 Receptor ◽  
Additional Risk ◽  
Ultraviolet Exposure ◽  
Skin Cancers ◽  
Increased Risk ◽  
Rising Incidence ◽  
The Impact ◽  
Common Malignancy ◽  
Melanoma Skin

Melanoma and non-melanoma skin cancers (NMSCs) are the most frequent cancers of the skin in white populations. An increased risk in the development of skin cancers has been associated with the combination of several environmental factors (i.e., ultraviolet exposure) and genetic background, including melanocortin-1 receptor (MC1R) status. In the last few years, advances in the diagnosis of skin cancers provided a great impact on clinical practice. Despite these advances, NMSCs are still the most common malignancy in humans and melanoma still shows a rising incidence and a poor prognosis when diagnosed at an advanced stage. Efforts are required to underlie the genetic and clinical heterogeneity of melanoma and NMSCs, leading to an optimization of the management of affected patients. The clinical implications of the impact of germline MC1R variants in melanoma and NMSCs’ risk, together with the additional risk conferred by somatic mutations in other peculiar genes, as well as the role of MC1R screening in skin cancers’ prevention will be addressed in the current review.

scholarly journals Human Papillomavirus-DNA Loads in Actinic Keratoses Exceed those in Non-Melanoma Skin Cancers

2005 ◽  
Vol 125 (1) ◽  
pp. 93-97 ◽  
Author(s):  
Soenke Jan Weissenborn ◽  
Ingo Nindl ◽  
Karin Purdie ◽  
Catherine Harwood ◽  
Charlotte Proby ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Actinic Keratoses ◽  
Skin Cancers ◽  
Papillomavirus Dna ◽  
Melanoma Skin
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