The Role of Human Papillomaviruses in the Development of Non-Melanoma Skin Cancers

2013 ◽  
Vol 33 (4) ◽  
pp. 1112-1118
Author(s):  
Havva Özge KESEROĞLU ◽  
Nilsel İLTER ◽  
Saliha ROTA ◽  
Sühan AYHAN ◽  
Gülendam BOZDAYI ◽  
...  
2016 ◽  
Vol 12 (1) ◽  
pp. 53-55
Author(s):  
P Anwar ◽  
S Mubashir ◽  
I Hassa ◽  
T Arif

Squamous cell carcinoma (SCC) of the skin is one of the most common non melanoma skin cancers (NMSC), along with basal cell carcinoma (BCC). Besides ultraviolet radiation, the role of exposure to industrial agents, ionizing radiation and areas of chronic inflammation is associated with the development of SCC. SCC may also be associated with foreign bodies. We report a rare case of cutaneous SCC in an elderly Kashmiri female, developing subsequent to subcutaneous non metallic foreign body, which was successfully excised with negative margins, and transposition flap closure. DOI: http://dx.doi.org/10.3126/njdvl.v12i1.10604 Nepal Journal of Dermatology, Venereology & Leprology Vol.12(1) 2014 pp.53-55


2009 ◽  
Vol 46 ◽  
pp. S43
Author(s):  
O. Keseroglu ◽  
N. Ilter ◽  
G. Bozdayi ◽  
S. Rota

1997 ◽  
pp. 748-758
Author(s):  
C. A. Harwood ◽  
J. Breuer ◽  
J. M. McGregor ◽  
C. M. Proby ◽  
A. Storey ◽  
...  

Genes ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 1093
Author(s):  
Michele Manganelli ◽  
Stefania Guida ◽  
Anna Ferretta ◽  
Giovanni Pellacani ◽  
Letizia Porcelli ◽  
...  

Melanoma and non-melanoma skin cancers (NMSCs) are the most frequent cancers of the skin in white populations. An increased risk in the development of skin cancers has been associated with the combination of several environmental factors (i.e., ultraviolet exposure) and genetic background, including melanocortin-1 receptor (MC1R) status. In the last few years, advances in the diagnosis of skin cancers provided a great impact on clinical practice. Despite these advances, NMSCs are still the most common malignancy in humans and melanoma still shows a rising incidence and a poor prognosis when diagnosed at an advanced stage. Efforts are required to underlie the genetic and clinical heterogeneity of melanoma and NMSCs, leading to an optimization of the management of affected patients. The clinical implications of the impact of germline MC1R variants in melanoma and NMSCs’ risk, together with the additional risk conferred by somatic mutations in other peculiar genes, as well as the role of MC1R screening in skin cancers’ prevention will be addressed in the current review.


Author(s):  
Morten Frisch

Penile cancers are rare primary malignancies located on the glans, foreskin, or shaft of the penis, excluding the urethra. The vast majority of penile cancers are epithelial tumors representing histological subtypes of squamous cell carcinoma (SCC). Most penile SCCs are believed to develop through pre-invasive lesions known as penile intraepithelial neoplasia and penile carcinoma in situ. They account for 0.1%–0.3% of all incident cancers (excluding non-melanoma skin cancers) in the United States and other developed countries and up to 1% of all cancers in some countries in sub-Saharan Africa. Penile cancers are rare in men younger than 40 years, and are typically diagnosed among men above age 60. The two most important risk factors are pathological phimosis and infection with high-risk types of human papillomaviruses (HPV), both of which are preventable conditions.


1999 ◽  
Vol 123 (11) ◽  
pp. 1015-1022
Author(s):  
David H. Persing ◽  
Franklyn G. Prendergast

Abstract A significant percentage of human cancers worldwide are associated with infections due to known viruses, including human papillomaviruses (cervical cancer and other skin cancers), human T-lymphotropic viruses (adult T-cell leukemias and lymphomas in endemic areas), hepatitis B virus (liver cancer), and Epstein-Barr virus (Burkitt lymphoma and nasopharyngeal carcinoma). The fraction of human cancers attributable to infection may now need to be revised in light of the fact that new viral associations have been discovered and other nonviral associations have been identified. This article addresses the increasingly recognized role of infectious agents as precipitants of human neoplasia and the possibility that novel diagnostic, therapeutic, and chemopreventive strategies may emanate directly from research directed at identifying and understanding these agents.


2018 ◽  
Author(s):  
Debra R. Garvey ◽  
Mary A. Ndiaye ◽  
Chandra K. Singh ◽  
Ambria Noll ◽  
Nihal Ahmad

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