P10-15 Tonic excitatory current mediated by ionotropic glycine receptors in the neonatal rat hippocampus

2010 ◽  
Vol 121 ◽  
pp. S163
Author(s):  
S.T. Sipila ◽  
K. Huttu ◽  
J. Voipio ◽  
K. Kaila
2014 ◽  
Vol 34 (30) ◽  
pp. 10003-10009 ◽  
Author(s):  
S. T. Sipila ◽  
A. Spoljaric ◽  
M. A. Virtanen ◽  
I. Hiironniemi ◽  
K. Kaila

2006 ◽  
Vol 24 (8) ◽  
pp. 589-589
Author(s):  
A. Falluel‐Morel ◽  
X. Zhou ◽  
E. Smith ◽  
H. Sisti ◽  
T. Shors ◽  
...  
Keyword(s):  

2011 ◽  
pp. P1-662-P1-662
Author(s):  
Thomas W Bastian ◽  
Jeremy Anderson ◽  
Stephanie J Fretham ◽  
Joseph R Prohaska ◽  
Michael K Georgieff ◽  
...  

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Camille Dumon ◽  
Yasmine Belaidouni ◽  
Diabe Diabira ◽  
Suzanne M. Appleyard ◽  
Gary A. Wayman ◽  
...  

Abstract The canonical physiological role of leptin is to regulate hunger and satiety acting on specific hypothalamic nuclei. Beyond this key metabolic function; leptin also regulates many aspects of development and functioning of neuronal hippocampal networks throughout life. Here we show that leptin controls chloride homeostasis in the developing rat hippocampus in vitro. The effect of leptin relies on the down-regulation of the potassium/chloride extruder KCC2 activity and is present during a restricted period of postnatal development. This study confirms and extends the role of leptin in the ontogenesis of functional GABAergic inhibition and helps understanding how abnormal levels of leptin may contribute to neurological disorders.


Neuroscience ◽  
2002 ◽  
Vol 110 (1) ◽  
pp. 19-28 ◽  
Author(s):  
H Vara ◽  
B Martı́nez ◽  
A Santos ◽  
A Colino

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