scholarly journals 253. A2UCOE-eGFP Confers Sustained Transgene Expression in Human Fetal Liver Hematopoietic Stem Cells (FL-HSC)

2011 ◽  
Vol 19 ◽  
pp. S98
Keyword(s):  
Stem Cells ◽  
Hematopoietic Stem Cells ◽  
Transgene Expression ◽  
Fetal Liver ◽  
Hematopoietic Stem ◽  
Human Fetal Liver

scholarly journals Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep.

1994 ◽  
Vol 93 (3) ◽  
pp. 1051-1055 ◽  
Author(s):  
E D Zanjani ◽  
A W Flake ◽  
H Rice ◽  
M Hedrick ◽  
M Tavassoli
Keyword(s):  
Stem Cells ◽  
Hematopoietic Stem Cells ◽  
Fetal Liver ◽  
Hematopoietic Stem ◽  
Human Fetal Liver

Long-term expansion of transplantable human fetal liver hematopoietic stem cells

Blood ◽  
2004 ◽  
Vol 103 (3) ◽  
pp. 1166-1170 ◽  
Author(s):  
Pierre Rollini ◽  
Stefan Kaiser ◽  
Eveline Faes-van't Hull ◽  
Ursula Kapp ◽  
Serge Leyvraz
Keyword(s):  
Stem Cells ◽  
Hematopoietic Stem Cells ◽  
Fetal Liver ◽  
Severe Combined Immunodeficiency ◽  
Culture Conditions ◽  
Hematopoietic Stem ◽  
Promising Alternative ◽  
Human Fetal Liver ◽  
Nonobese Diabetic

AbstractHematopoietic stem cells (HSCs), with their dual ability for self-renewal and multilineage differentiation, constitute an essential component of hematopoietic transplantations. Human fetal liver (FL) represents a promising alternative HSC source, and we previously reported simple culture conditions allowing long-term expansion of FL hematopoietic progenitors. In the present study, we used the nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse xenotransplantation assay to confirm that human FL is rich in NOD/SCID-repopulating cells (SRCs) and to show that these culture conditions repeatedly maintained short- and long-term SRCs from various FL samples for at least 28 days. Quantitative limited dilution analysis in NOD/SCID mice demonstrated for the first time that a 10- to over a 100-fold net expansion of FL SRCs could be achieved after 28 days of culture. The efficiency of this culture system may lead to an increase in the use of FL as a source of HSCs for transplantation in adult patients, as previously demonstrated with umbilical cord blood under different culture conditions. (Blood. 2004;103:1166-1170)

3139 – TRANSCRIPTIONAL, PROTEIN-LEVEL AND FUNCTIONAL PROFILING OF HUMAN FETAL LIVER-DERIVED HEMATOPOIETIC STEM CELLS AT SINGLE CELL RESOLUTION

2020 ◽  
Vol 88 ◽  
pp. S81
Author(s):  
Kim Vanuytsel ◽  
Carlos Villacorta Martin ◽  
Jonathan Lindstrom-Vautrin ◽  
Zhe Wang ◽  
Wilfredo Garcia Beltran ◽  
...  
Keyword(s):  
Stem Cells ◽  
Hematopoietic Stem Cells ◽  
Single Cell ◽  
Protein Level ◽  
Fetal Liver ◽  
Hematopoietic Stem ◽  
Human Fetal Liver ◽  
Functional Profiling

scholarly journals Endothelial protein C receptor (EPCR) expression marks human fetal liver hematopoietic stem cells

Haematologica ◽  
2018 ◽  
Vol 104 (2) ◽  
pp. e47-e50 ◽  
Author(s):  
Agatheeswaran Subramaniam ◽  
Mehrnaz Safaee Talkhoncheh ◽  
Mattias Magnusson ◽  
Jonas Larsson
Keyword(s):  
Stem Cells ◽  
Hematopoietic Stem Cells ◽  
Protein C ◽  
Fetal Liver ◽  
Endothelial Protein C Receptor ◽  
Hematopoietic Stem ◽  
Human Fetal Liver

scholarly journals Transplantable hematopoietic stem cells in human fetal liver have a CD34+ side population (SP)phenotype

2001 ◽  
Vol 108 (7) ◽  
pp. 1071-1077 ◽  
Author(s):  
Naoyuki Uchida ◽  
Tomoaki Fujisaki ◽  
Allen C. Eaves ◽  
Connie J. Eaves
Keyword(s):  
Stem Cells ◽  
Hematopoietic Stem Cells ◽  
Fetal Liver ◽  
Side Population ◽  
Hematopoietic Stem ◽  
Human Fetal Liver

Immunophenotypic characterization of human fetal liver hematopoietic stem cells during the midtrimester of gestation

1997 ◽  
Vol 177 (3) ◽  
pp. 619-625 ◽  
Author(s):  
Jerry M. Gilles ◽  
M.Y. Divon ◽  
Eric Bentolila ◽  
Ohad D. Rotenberg ◽  
Dave F. Gebhard ◽  
...  
Keyword(s):  
Stem Cells ◽  
Hematopoietic Stem Cells ◽  
Fetal Liver ◽  
Hematopoietic Stem ◽  
Human Fetal Liver

scholarly journals The Role of Mitochondrial and Oxidative Injury in BDE 47 Toxicity to Human Fetal Liver Hematopoietic Stem Cells

2007 ◽  
Vol 101 (1) ◽  
pp. 81-90 ◽  
Author(s):  
Jing Shao ◽  
Collin C. White ◽  
Michael J. Dabrowski ◽  
Terrance J. Kavanagh ◽  
Melissa L. Eckert ◽  
...  
Keyword(s):  
Stem Cells ◽  
Hematopoietic Stem Cells ◽  
Fetal Liver ◽  
Oxidative Injury ◽  
Hematopoietic Stem ◽  
Human Fetal Liver
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