scholarly journals 898. Non-Viral Gene Delivery into Rat Spinal Cord: Paraspinal Injection

2002 ◽  
Vol 5 (5) ◽  
pp. S293
Keyword(s):  
Spinal Cord ◽  
Gene Delivery ◽  
Viral Gene ◽  
Rat Spinal Cord ◽  
Viral Gene Delivery

Recent advances in the analysis full/empty capsid ratio and genome integrity of adeno-associated virus (AAV) gene delivery vectors

2020 ◽  
Vol 20 ◽  
Author(s):  
L. Hajba ◽  
A. Guttman
Keyword(s):  
Gene Delivery ◽  
High Efficiency ◽  
Analytical Techniques ◽  
Viral Gene ◽  
Adeno Associated Virus ◽  
Gene Delivery Vectors ◽  
Empty Capsid ◽  
Purification Methods ◽  
Viral Gene Delivery

: Adeno-associated virus (AAV) is one of the most promising viral gene delivery vectors with long-term gene expression and disease correction featuring high efficiency and excellent safety in human clinical trials. During the production of AAV vectors,there are several quality control (QC)parameters that should be rigorously monitored to comply with clini-cal safety and efficacy. This review gives a short summary of the most frequently used AVV production and purification methods,focusing on the analytical techniques applied to determine the full/empty capsid ratio and the integrity of the encapsidated therapeutic DNA of the products.

Non-viral gene delivery to atelectatic and ventilated lungs

2002 ◽  
Vol 73 (2) ◽  
pp. 432-437 ◽  
Author(s):  
Uz Stammberger ◽  
Aima N. Uduehi ◽  
Bartosz Kubisa ◽  
Thierry Roth ◽  
Ralph A. Schmid
Keyword(s):  
Gene Delivery ◽  
Viral Gene ◽  
Viral Gene Delivery

Modulating polymer chemistry to enhance non-viral gene delivery inside hydrogels with tunable matrix stiffness

Biomaterials ◽  
2013 ◽  
Vol 34 (37) ◽  
pp. 9657-9665 ◽  
Author(s):  
Michael Keeney ◽  
Sheila Onyiah ◽  
Zhe Zhang ◽  
Xinming Tong ◽  
Li-Hsin Han ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Polymer Chemistry ◽  
Viral Gene ◽  
Matrix Stiffness ◽  
Viral Gene Delivery
Sign in / Sign up

Export Citation Format

Share Document