scholarly journals Three-dimensional scaffold platform for controlled therapeutic drug and non-viral gene delivery to enhance nerve regeneration and remyelination in spinal cord injuries

2018 ◽  
Author(s):  
◽  
Lan Huong Nguyen
Keyword(s):  
Spinal Cord ◽  
Gene Delivery ◽  
Nerve Regeneration ◽  
Spinal Cord Injuries ◽  
Three Dimensional ◽  
Therapeutic Drug ◽  
Viral Gene ◽  
Viral Gene Delivery

Non-viral gene delivery carrier and its three-dimensional transfection system

2010 ◽  
Vol 386 (1-2) ◽  
pp. 232-242 ◽  
Author(s):  
Cai-Xia He ◽  
Yasuhiko Tabata ◽  
Jian-Qing Gao
Keyword(s):  
Gene Delivery ◽  
Three Dimensional ◽  
Viral Gene ◽  
Viral Gene Delivery

Recent advances in the analysis full/empty capsid ratio and genome integrity of adeno-associated virus (AAV) gene delivery vectors

2020 ◽  
Vol 20 ◽  
Author(s):  
L. Hajba ◽  
A. Guttman
Keyword(s):  
Gene Delivery ◽  
High Efficiency ◽  
Analytical Techniques ◽  
Viral Gene ◽  
Adeno Associated Virus ◽  
Gene Delivery Vectors ◽  
Empty Capsid ◽  
Purification Methods ◽  
Viral Gene Delivery

: Adeno-associated virus (AAV) is one of the most promising viral gene delivery vectors with long-term gene expression and disease correction featuring high efficiency and excellent safety in human clinical trials. During the production of AAV vectors,there are several quality control (QC)parameters that should be rigorously monitored to comply with clini-cal safety and efficacy. This review gives a short summary of the most frequently used AVV production and purification methods,focusing on the analytical techniques applied to determine the full/empty capsid ratio and the integrity of the encapsidated therapeutic DNA of the products.

Non-viral gene delivery to atelectatic and ventilated lungs

2002 ◽  
Vol 73 (2) ◽  
pp. 432-437 ◽  
Author(s):  
Uz Stammberger ◽  
Aima N. Uduehi ◽  
Bartosz Kubisa ◽  
Thierry Roth ◽  
Ralph A. Schmid
Keyword(s):  
Gene Delivery ◽  
Viral Gene ◽  
Viral Gene Delivery
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