Abstract
Background: Strain rate (SR) is one of the most used techniques to study left atrial (LA) although it requires post processing of the images, a learning curve and additional software, Tissue Doppler Imaging (TDI) is widely available and easy to use, TDI could detect changes in LA function associated with age similar to other parameters. The aim of this to evaluate lateral LA wall by DTI and SR, according to different age decades and compare them and with other parameters of diastolic function in a population of adults without cardiovascular disease. Materials and Methods: 91 healthy adults were prospectively evaluated. In apical 4-chambers view the LA lateral wall was divided into three portions. Peak velocities of basal and mid portions were measured with pulsed‐wave TDI color on line and SRI by speckle tracking. A first positive wave ( S'la and SRS) and two negative waves ( E'la and SRE, and A'la and SRA respectively) were obtained. E'la/A'la ratio and SRE/SRA ratio were analyzed. The distribution of the variables by age subgroups was described and analyzed. Correlation analyses were performed. Results: The median age was 42 years and 54.9% were female. E'la/A'la show a positive good correlation with age. E'la/A'la and SRE/SRA ratios changed from > 1 to < 1 in the age group of 41-50 years, while this occurred in the group of 51-60 years for the E/A ratio. Lateral and septal mitral annulus E´ show decrease with age and prolongation of E -wave deceleration time was observed in the age group over 61 years.Conclusion Normal values according to age group of TDI of the LA lateral wall were obtained. Age-related changes in LA function could be detected as early with TDI as with SRI. Future studies are required to explore if TDI could be used as an alternative to SRI in other populations.
996 Can tissue Doppler imaging of the lateral mitral annulus, quantify left atrial contractile function in patients with severe mitral regurgitation due to mitral valve prolapse?
