486 Effects of nitroglycerin therapy on reduction of vena contracta width in mitral regurgitation

1999 ◽  
Vol 1 ◽  
pp. S83-S83
Author(s):  
T KATOVA ◽  
V YOTOVA
Cardiology ◽  
2015 ◽  
Vol 130 (2) ◽  
pp. 82-86
Author(s):  
H.M. Gunes ◽  
G.B. Guler ◽  
E. Guler ◽  
G.G. Demir ◽  
S. Hatipoglu ◽  
...  

Objective: Osteopontin (OPN), a sialoprotein present within atherosclerotic lesions, especially in calcified plaques, is linked to the progression of coronary artery disease and heart failure. We assessed the impact of valve surgery on serum OPN and left ventricular (LV) function in patients with mitral regurgitation (MR). Methods: Thirty-two patients with severe MR scheduled for surgery were included in the study. Echocardiography markers were assessed preoperatively and at 3 months following the surgery and matched with the serum OPN levels. Results: Valve surgery was associated with a reduction of the ejection fraction (EF) from 55.2 ± 6.3 to 48.8 ± 7.1% after surgery, p < 0.001. Following surgery, the OPN level was significantly higher than preoperatively (mean 245, range 36-2,284 ng/ml vs. 76, 6-486 ng/ml, p = 0.007). Preoperative OPN exhibited a slight negative correlation with the EF (r = -0.35, p = 0.04), and a moderate correlation with vena contracta (r = -0.38, p = 0.02). There were no other meaningful correlations between conventional echocardiographic parameters and OPN. Conclusion: Following valve surgery due to severe MR, patients exhibited a decrease in EF and an increase in OPN levels. The assessment of preoperative OPN failed to strongly predict probable LV dysfunction.


2011 ◽  
Vol 12 (04) ◽  
pp. 234-238 ◽  
Author(s):  
Shiro Nozaki ◽  
Katsufumi Mizushige ◽  
Tomohiko Taminato ◽  
Hirohide Matsuo

2014 ◽  
Vol 28 (4) ◽  
pp. 1206-1213 ◽  
Author(s):  
M. Di Marcello ◽  
E. Terzo ◽  
C. Locatelli ◽  
V. Palermo ◽  
E. Sala ◽  
...  

2018 ◽  
Vol 6 (3) ◽  
pp. 29
Author(s):  
Mehrnoush Toufan ◽  
Dina Ashouri

Dear Editor, Two-dimensional (2D) echocardiography is a powerful tool for assessment of mitral regurgitation (MR) [1]. However, it bears several major disadvantages. Evidence suggests that measurement of the vena contracta area (VCA) via a three-dimensional (3D) method is significantly more accurate than 2D methods in the quantification of MR since the 2D method is not sufficiently reliable in calculation of VC diameter because of  circular assumption of VC area [2]. VCA direct planimetry (DP) and multiplanar reconstruction (MPR)-derived VCA are direct and reliable methods to quantify MR severity, and their results are comparable with those of 2D integrative method [2, 3]. It is strongly recommended that these methods especially DP can replace 2D methods in the quantification of MR in the clinical practice, as it is more accurate and easy to perform [3].


1998 ◽  
Vol 31 ◽  
pp. 385
Author(s):  
A.M. Kizilbash ◽  
D.L. Willett ◽  
M.E. Brickner ◽  
I. Afndi ◽  
S.K. Heinle ◽  
...  

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