Abstract #1091: Chronic Hypoparathyroidism Disease Profile: Initial Analysis from the Paradighm™ Natural History Global Registry

2017 ◽  
Vol 23 ◽  
pp. 260-261
Author(s):  
Steven Ing ◽  
Bart Clarke ◽  
Aliya Khan ◽  
Michael Mannstadt ◽  
Michael McDermott ◽  
...  
2017 ◽  
Author(s):  
Bart L Clarke ◽  
Steven Ing ◽  
Aliya Khan ◽  
Michael Mannstadt ◽  
Michael McDermott ◽  
...  

Author(s):  
Matt Woodburn ◽  
Deborah L Paul ◽  
Wouter Addink ◽  
Steven J Baskauf ◽  
Stanley Blum ◽  
...  

Digitisation and publication of museum specimen data is happening worldwide, but far from complete. Museums can start by sharing what they know about their holdings at a higher level, long before each object has its own record. Information about what is held in collections worldwide is needed by many stakeholders including collections managers, funders, researchers, policy-makers, industry, and educators. To aggregate this information from collections, the data need to be standardised (Johnston and Robinson 2002). So, the Biodiversity Information Standards (TDWG) Collection Descriptions (CD) Task Group is developing a data standard for describing collections, which gives the ability to provide: automated metrics, using standardised collection descriptions and/or data derived from specimen datasets (e.g., counts of specimens) and a global registry of physical collections (i.e., digitised or non-digitised). automated metrics, using standardised collection descriptions and/or data derived from specimen datasets (e.g., counts of specimens) and a global registry of physical collections (i.e., digitised or non-digitised). Outputs will include a data model to underpin the new standard, and guidance and reference implementations for the practical use of the standard in institutional and collaborative data infrastructures. The Task Group employs a community-driven approach to standard development. With international participation, workshops at the Natural History Museum (London 2019) and the MOBILISE workshop (Warsaw 2020) allowed over 50 people to contribute this work. Our group organized online "barbecues" (BBQs) so that many more could contribute to standard definitions and address data model design challenges. Cloud-based tools (e.g., GitHub, Google Sheets) are used to organise and publish the group's work and make it easy to participate. A Wikibase instance is also used to test and demonstrate the model using real data. There are a range of global, regional, and national initiatives interested in the standard (see Task Group charter). Some, like GRSciColl (now at the Global Biodiversity Information Facility (GBIF)), Index Herbariorum (IH), and the iDigBio US Collections List are existing catalogues. Others, including the Consortium of European Taxonomic Facilities (CETAF) and the Distributed System of Scientific Collections (DiSSCo), include collection descriptions as a key part of their near-term development plans. As part of the EU-funded SYNTHESYS+ project, GBIF organized a virtual workshop: Advancing the Catalogue of the World's Natural History Collections to get international input for such a resource that would use this CD standard. Some major complexities present themselves in designing a standardised approach to represent collection descriptions data. It is not the first time that the natural science collections community has tried to address them (see the TDWG Natural Collections Description standard). Beyond natural sciences, the library community in particular gave thought to this (Heaney 2001, Johnston and Robinson 2002), noting significant difficulties. One hurdle is that collections may be broken down into different degrees of granularity according to different criteria, and may also overlap so that a single object can be represented in more than one collection description. Managing statistics such as numbers of objects is complex due to data gaps and variable degrees of certainty about collection contents. It also takes considerable effort from collections staff to generate structured data about their undigitised holdings. We need to support simple, high-level collection summaries as well as detailed quantitative data, and to be able to update as needed. We need a simple approach, but one that can also handle the complexities of data, scope, and social needs, for digitised and undigitised collections. The data standard itself is a defined set of classes and properties that can be used to represent groups of collection objects and their associated information. These incorporate common characteristics ('dimensions') by which we want to describe, group and break down our collections, metrics for quantifying those collections, and properties such as persistent identifiers for tracking collections and managing their digital counterparts. Existing terms from other standards (e.g. Darwin Core, ABCD) are re-used if possible. The data model (Fig. 1) underpinning the standard defines the relationships between those different classes, and ensures that the structure as well as the content are comparable across different datasets. It centres around the core concept of an 'object group', representing a set of physical objects that is defined by one or more dimensions (e.g., taxonomy and geographic origin), and linked to other entities such as the holding institution. To the object group, quantitative data about its contents are attached (e.g. counts of objects or taxa), along with more qualitative information describing the contents of the group as a whole. In this presentation, we will describe the draft standard and data model with examples of early adoption for real-world and example data. We will also discuss the vision of how the new standard may be adopted and its potential impact on collection discoverability across the collections community.


2019 ◽  
Vol 25 (8) ◽  
pp. S90
Author(s):  
Michela Brambatti ◽  
Boss Le ◽  
Galiela Macias ◽  
Yasmeen Esshaki ◽  
Victor Escobedo ◽  
...  

Author(s):  
Patrick Semal ◽  
Marielle Adam ◽  
Didier Van den Spiegel ◽  
Franck Theeten ◽  
Henry Engledow ◽  
...  

Several initiatives aim to map the diversity of Natural History (NH) collections and standardise their descriptions. The Global Registry of Biodiversity Repositories (GRBio) is the most recent global registry. Unfortunately the server has been down since mid-2018 but the Global Biodiversity Information Facility (GBIF) recently "rescued" this data. In addition to this, the One World Collection exercise is a set of high-level collection descriptors (size, group coverage and geographic distribution) supporting a common strategy between the largest world institutions. Despite these efforts, a large part of the NH collections remains digitally unavailable and digitisation at the specimen level will take several decades. A new NH collections dashboard is needed in order to harmonise the efforts of the institutions. The Consortium of European Taxonomic Facilities (CETAF) is a good place to introduce this excercise. CETAF’s members hold over half of the world’s NH collections, representing 80% of the world's bio- and geo-diversity. Most of these collections are now engaged in the preparation for the common process of the Distributed System of Scientific Collections (DiSSCo, European Strategy Forum on Research Infrastructure). Additionally in Belgium, the Royal Belgian Institute of Natural Sciences (RBINS), Royal Museum of Central Africa (RMCA), Meise Botanic Garden (MBG) and CETAF have joined efforts to set up a common research portal (Natural Heritage, BRAIN-be project). The goal is to link together several collection management systems (CMS) and to (re)create links between isolated collection items. The CETAF collections dashboard splits the information into small metadata units related to topics relevant to the collections (taxonomy, geographic distribution, digitisation strategy and coverage, stratigraphy, etc.). The model allows for the creation of new units without a complete modification of the database structure. All units are defined by the Dublin Core and by fields derived from the Innovation and consolidation for large scale digitisation of natural heritage (ICEDIG) d2.3 deliverable (van Egmond et al. 2019). The object hierarchy allows for the creation of sub-collections and preserves the unity of the information. The CMS has an internal object database with a full index and a faceted search interface. It also has web services and XLS (Microsoft® Excel®) import/export functionalities. The collection dashboard also includes a complete workflow and access rights management at the object level. This is important for the information that is protected by the EU General Data Protection Regulation (GDPR). The dashboard is now being evaluated with the collections hosted by the partners of Natural Heritage. The system will be proposed to CETAF members and connections will be established with the international portals such as the GBIF or the future DiSSCo portal.


2014 ◽  
Author(s):  
Steven Bowlin ◽  
Tara Sadowski ◽  
Tamara Vokes ◽  
John Bilezikian ◽  
Bart Clarke ◽  
...  

2020 ◽  
Vol 43 ◽  
Author(s):  
Hannes Rakoczy

Abstract The natural history of our moral stance told here in this commentary reveals the close nexus of morality and basic social-cognitive capacities. Big mysteries about morality thus transform into smaller and more manageable ones. Here, I raise questions regarding the conceptual, ontogenetic, and evolutionary relations of the moral stance to the intentional and group stances and to shared intentionality.


Author(s):  
E.L. Benedetti ◽  
I. Dunia ◽  
Do Ngoc Lien ◽  
O. Vallon ◽  
D. Louvard ◽  
...  

In the eye lens emerging molecular and structural patterns apparently cohabit with the remnants of the past. The lens in a rather puzzling fashion sums up its own natural history and even transient steps of the differentiation are memorized. A prototype of this situation is well outlined by the study of the lenticular intercellular junctions. These membrane domains exhibit structural, biochemical and perhaps functional polymorphism reflecting throughout life the multiple steps of the differentiation of the epithelium into fibers and of the ageing process of the lenticular cells.The most striking biochemical difference between the membrane derived from the epithelium and from the fibers respectively, concerns the presence of the 26,000 molecular weight polypeptide (MP26) in the latter membranes.


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