738 End-stage chronic heart failure secondary to IDC is accompanied by severely depressed coronary flow reserve

2005 ◽  
Vol 4 (1) ◽  
pp. 163-164
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Flow Reserve ◽  
End Stage

Chronic Heart Failure: Global Left Ventricular Perfusion and Coronary Flow Reserve with Velocity-encoded Cine MR Imaging: Initial Results

Radiology ◽  
2003 ◽  
Vol 227 (1) ◽  
pp. 209-215 ◽  
Author(s):  
Gunnar K. Lund ◽  
Norbert Watzinger ◽  
Maythem Saeed ◽  
Gautham P. Reddy ◽  
Ming Yang ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Mr Imaging ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Left Ventricular ◽  
Global Left Ventricular ◽  
Flow Reserve ◽  
Cine Mr ◽  
Initial Results

scholarly journals Coronary flow reserve as a link between diastolic and systolic function and exercise capacity in heart failure

2012 ◽  
Vol 14 (7) ◽  
pp. 677-683 ◽  
Author(s):  
M. Snoer ◽  
T. Monk-Hansen ◽  
R. H. Olsen ◽  
L. R. Pedersen ◽  
O. W. Nielsen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Exercise Capacity ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Systolic Function ◽  
Flow Reserve

Increased inactivation of nitric oxide is involved in impaired coronary flow reserve in heart failure

2001 ◽  
Vol 281 (6) ◽  
pp. H2619-H2625 ◽  
Author(s):  
Ryo Nakamura ◽  
Kensuke Egashira ◽  
Kenichi Arimura ◽  
Youji Machida ◽  
Tomomi Ide ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Lipid Peroxide ◽  
Canine Model ◽  
Oxygen Free Radical ◽  
Resonance Spectroscopy ◽  
Synthesis Inhibitor ◽  
Flow Reserve

Recent evidence suggests that increased inactivation of endothelium-derived nitric oxide (NO) by oxygen free radical (OFR) formation is involved in the pathogenesis of endothelial dysfunction in heart failure (HF). However, it is unclear whether increased OFR limits coronary flow reserve in HF. To test this hypothesis, we examined the effects of antioxidant therapy on coronary flow reserve in a canine model of tachycardia-induced HF. The flow reserve (percent increase in coronary blood flow) to adenosine or to 20-s ischemia was less and OFR formation (electron-spin resonance spectroscopy) in myocardial tissues was greater in HF dogs than in controls. Immunohistochemical staining of 4-hydroxy-2-nonenal, an OFR-induced lipid peroxide, was detected in coronary microvessels of HF dogs. Intracoronary infusion of a cell-permeable OFR scavenger, tiron, suppressed OFR formation and improved the vasodilating capacity to adenosine or brief ischemia in HF dogs but not in controls. A NO synthesis inhibitor, N G-monomethyl-l-arginine (l-NMMA), diminished the beneficial effects of tiron in HF dogs. Vasodilation to sodium nitroprusside was similar between control and HF dogs, and no change in its response was noted with tiron or tiron + l-NMMA in either group. In summary, antioxidant treatment with tiron improved coronary flow reserve by increasing NO bioactivity in HF dogs. Thus increased OFR formation may impair coronary flow reserve in HF by reducing NO bioactivity.

Effects of Rosuvastatin on Coronary Flow Reserve and Metabolic Mismatch in Patients With Heart Failure (from the CORONA Study)

2010 ◽  
Vol 105 (4) ◽  
pp. 517-521 ◽  
Author(s):  
Pim van der Harst ◽  
Riemer H.J.A. Slart ◽  
Rene A. Tio ◽  
Peter H.J.M. Dunselman ◽  
Antoon T.M. Willemsen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Flow Reserve ◽  
Patients With Heart Failure

scholarly journals Ischemic heart failure mortality is not predicted by cardiac insulin resistance but by diabetes perse and coronary flow reserve: A retrospective dynamic cardiac 18F-FDG PET study

Metabolism ◽  
2021 ◽  
pp. 154862
Author(s):  
Thien Vinh Luong ◽  
Mette Glavind Bülow Pedersen ◽  
Mette Louise Blouner Gram Kjærulff ◽  
Simon Madsen ◽  
Katrine Meyer Lauritsen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Insulin Resistance ◽  
Coronary Flow Reserve ◽  
Fdg Pet ◽  
Coronary Flow ◽  
Ischemic Heart ◽  
Ischemic Heart Failure ◽  
Flow Reserve ◽  
18F Fdg
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