scholarly journals 92 Early treatment with inhaled antibiotics postpones recurrence of Achromobacter species in cystic fibrosis

2013 ◽  
Vol 12 ◽  
pp. S72
Author(s):  
M. Wang ◽  
W. Ridderberg ◽  
C.R. Hansen ◽  
N. Høiby ◽  
S. Jensen-Fangel ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Early Treatment ◽  
Inhaled Antibiotics

scholarly journals Early treatment with inhaled antibiotics postpones next occurrence of Achromobacter in cystic fibrosis

2013 ◽  
Vol 12 (6) ◽  
pp. 638-643 ◽  
Author(s):  
M. Wang ◽  
W. Ridderberg ◽  
C.R. Hansen ◽  
N. Høiby ◽  
S. Jensen-Fangel ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Early Treatment ◽  
Inhaled Antibiotics

Clinical Characteristics and Early Treatment Patterns of Newly Diagnosed Cystic Fibrosis–Related Diabetes in Two Tertiary Centers

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2374-PUB
Author(s):  
ERIN MCCORRY ◽  
HIBA BASHEER ◽  
JORGE E. LASCANO ◽  
JOHN YOON ◽  
JULIO A. LEEY
Keyword(s):  
Cystic Fibrosis ◽  
Early Treatment ◽  
Clinical Characteristics ◽  
Treatment Patterns ◽  
Newly Diagnosed

scholarly journals Cystic fibrosis in young children: A review of disease manifestation, progression, and response to early treatment

2016 ◽  
Vol 15 (2) ◽  
pp. 147-157 ◽  
Author(s):  
Donald R. VanDevanter ◽  
Jennifer S. Kahle ◽  
Amy K. O’Sullivan ◽  
Slaven Sikirica ◽  
Paul S. Hodgkins
Keyword(s):  
Cystic Fibrosis ◽  
Young Children ◽  
Early Treatment ◽  
Disease Manifestation

Case 13

2020 ◽  
pp. 81-86
Author(s):  
Hilary Humphreys
Keyword(s):  
Cystic Fibrosis ◽  
Stenotrophomonas Maltophilia ◽  
New Technologies ◽  
Microbiology Laboratory ◽  
Oral Antibiotics ◽  
Flight Mass Spectrometry ◽  
Single Room ◽  
Inhaled Antibiotics ◽  
True Infection ◽  
Opportunist Pathogen

There is an increasing number of opportunist pathogens that may cause acute pulmonary exacerbations of cystic fibrosis as the patient cohort survives longer. However, it can often be difficult to determine if the isolation of these bacteria represents colonization or true infection. Their identification from sputum samples in the microbiology laboratory is also challenging, requires significant scientific expertise, and is assisted by new technologies such as MALDI-TOF (matrix-assisted laser desorption/ionization time-of-flight mass spectrometry). One such opportunist pathogen is Stenotrophomonas maltophilia, for which risk factors include increasing age and recent oral antibiotics, especially carbapenems. However, it is unclear if this bacterium is transmitted from patient to patient unlike with Pseudomonas aeruginosa, but all patients with cystic fibrosis should be admitted to a single room when hospitalization is required. Controversies exist regarding the optimal treatment which in the future may include a greater reliance on inhaled antibiotics.

scholarly journals Microbiological contamination of nebulizers used by cystic fibrosis patients: an underestimated problem

2019 ◽  
Vol 45 (3) ◽  
Author(s):  
Barbara Riquena ◽  
Luciana de Freitas Velloso Monte ◽  
Agnaldo José Lopes ◽  
Luiz Vicente Ribeiro Ferreira da Silva-Filho ◽  
Neiva Damaceno ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Burkholderia Cepacia ◽  
Tap Water ◽  
Significant Proportion ◽  
Burkholderia Cepacia Complex ◽  
Structured Interviews ◽  
Candida Spp ◽  
Cross Sectional ◽  
Inhaled Antibiotics ◽  
Cleaning And Disinfection

ABSTRACT Objective: Home nebulizers are routinely used in the treatment of patients with cystic fibrosis (CF). This study aims to evaluate the contamination of nebulizers used for CF patients, that are chronically colonized by Pseudomonas aeruginosa, and the association of nebulizer contamination with cleaning, decontamination and drying practices. Methods: A cross-sectional, observational, multicenter study was conducted in seven CF reference centers in Brazil to obtain data from medical records, structured interviews with patients/caregivers were performed, and nebulizer’s parts (interface and cup) were collected for microbiological culture. Results: overall, 77 CF patients were included. The frequency of nebulizer contamination was 71.6%. Candida spp. (52.9%), Stenotrophomonas maltophilia (11.9%), non-mucoid P. aeruginosa (4.8%), Staphylococcus aureus (4.8%) and Burkholderia cepacia complex (2.4%) were the most common isolated pathogens. The frequency of nebulizers’ hygiene was 97.4%, and 70.3% of patients reported cleaning, disinfection and drying the nebulizers. The use of tap water in cleaning method and outdoor drying of the parts significantly increased (9.10 times) the chance of nebulizers’ contamination. Conclusion: Despite the high frequency hygiene of the nebulizers reported, the cleaning and disinfection methods used were often inadequate. A significant proportion of nebulizers was contaminated with potentially pathogenic microorganisms for CF patients. These findings support the need to include patients/caregivers in educational programs and / or new strategies for delivering inhaled antibiotics.

scholarly journals 97 Early treatment of first Pseudomonas aeruginosa isolation in Cystic Fibrosis patients

2006 ◽  
Vol 5 ◽  
pp. S21
Author(s):  
S. Gartner ◽  
C. Martin ◽  
N. Cobos ◽  
G. Vizmanos ◽  
A. Ferrer ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Pseudomonas Aeruginosa ◽  
Early Treatment

Efficacy and safety of inhaled antibiotics for chronicpseudomonasinfection in cystic fibrosis: Network meta-analysis

2016 ◽  
Author(s):  
Stuart Elborn ◽  
Anne-Lise Vataire ◽  
Ayako Fukushima ◽  
Samuel Aballéa ◽  
Amine Khemiri ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Meta Analysis ◽  
Efficacy And Safety ◽  
Inhaled Antibiotics
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