234 INFLUENCE OF TUMOR SIZE ON PROGRESSION FREE AND OVERALL SURVIVAL IN A COHORT OF CONSECUTIVE RENAL CELL CANCER PATIENTS WITH LONG-TERM FOLLOW UP

2009 ◽  
Vol 8 (4) ◽  
pp. 179
Author(s):  
S. Zastrow ◽  
I. Von Bar ◽  
M.O. Grimm ◽  
M. Fröhner ◽  
S. Leike ◽  
...  
2005 ◽  
Vol 23 (16_suppl) ◽  
pp. 4597-4597
Author(s):  
V. K. Chand ◽  
J. Sidloski ◽  
G. Clamon ◽  
R. J. Hohl

2020 ◽  
Author(s):  
Annemarie Uhlig ◽  
Johannes Uhlig ◽  
Lutz Trojan ◽  
Michael Woike ◽  
Marianne Leitsmann ◽  
...  

The aim of this study was to evaluate the association between axitinib, sunitinib and temsirolimus toxicities and patient survival in metastatic renal cell cancer patients. Overall survival (OS) and progression-free survival (PFS) of metastatic renal cell cancer patients from the prospective multicenter STAR-TOR study were assessed using multivariable Cox models. A total of 1195 patients were included (n = 149 axitinib; n = 546 sunitinib; n = 500 temsirolimus). The following toxicities significantly predicted outcomes: hand–foot skin reaction (hazard ratio [HR] = 0.29) for PFS with axitinib; stomatitis (HR = 0.62) and pneumonitis (HR = 0.23) for PFS with temsirolimus; stomatitis (HR = 0.52) and thrombocytopenia (HR = 0.6) for OS with temsirolimus; fatigue (HR = 0.71) for PFS with sunitinib; hand–foot skin reaction (HR = 0.56) and fatigue (HR = 0.58) for OS with sunitinib. In conclusion, in metastatic renal cell cancer, axitinib, sunitinib and temsirolimus demonstrate specific toxicities that are protective OS/PFS predictors.


2013 ◽  
Vol 4 (2) ◽  
pp. 45 ◽  
Author(s):  
Emmanuel Abara ◽  
Iolanda Chivulescu ◽  
Nilam Clerk ◽  
Pablo Cano ◽  
Alexis Goth

Localized renal cell carcinoma (RCC) responds well to surgery.Patients often question how long they have to be on surveillanceafter their surgery. Several follow-up patterns have been describedin the literature. Until 2009, no published established Canadianguidelines existed to assist Canadian health-care practitioners inthe surveillance of these patients. We present 3 cases of RCC thatrecurred 10 years or longer after the initial nephrectomy. Thesecases emphasize the need for careful long-term follow-up, as recommendedin the Canadian Urological Association guidelines.We also discuss the optimism of prolonged disease survival inthe era of novel therapeutic agents that target angiogenesis.


2005 ◽  
Vol 23 (1) ◽  
pp. 50-54 ◽  
Author(s):  
M. Kuczyk ◽  
G. Wegener ◽  
A. S. Merseburger ◽  
A. Anastasiadis ◽  
S. Machtens ◽  
...  

Author(s):  
Kaisa Sunela ◽  
Matti Kataja ◽  
Eero Lehtinen ◽  
Tapio Salminen ◽  
Paula Kujala ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document