Risk factors of recurrence and de novo incontinence following endoscopic treatment of vesico-urethral anastomotic stenosis

Abstract. Background: In this study, we investigated the patency of endovascular stent grafts in haemodialysis patients with arteriovenous grafts, the modes of patency loss, and the risk factors for re-intervention. Patients and methods: Haemodialysis patients with graft-vein anastomotic stenosis of their arteriovenous grafts who were treated with endovascular stent-grafts between 2008 and 2013 were entered into this retrospective study. Primary and secondary patency, modes of patency loss, and risk factors for intervention were recorded. Results: Cumulative circuit primary patency rates decreased from 40.0 % at 6 months to 7.3 % at 24 months. Cumulative target lesion primary patency rates decreased from 72.1 % at 6 months to 22.0 % at 24 months. Cumulative secondary patency rates decreased from 81.3 % at 12 months to 31.6 % at 36 months. Patients with a history of cerebrovascular accident had a significantly higher risk of secondary patency loss, and graft puncture site stenosis jeopardised the results of stent-graft treatment. Conclusions: Our data can help to improve outcomes in haemodialysis patients treated with stent-grafts for venous anastomosis of an arteriovenous graft.

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Risk of hemorrhage from de novo cerebral aneurysms

Journal of Neurosurgery ◽

10.3171/2012.9.jns111512 ◽

2013 ◽

Vol 118 (1) ◽

pp. 58-62 ◽

Cited By ~ 22

Author(s):

William J. Kemp ◽

Daniel H. Fulkerson ◽

Troy D. Payner ◽

Thomas J. Leipzig ◽

Terry G. Horner ◽

...

Keyword(s):

Risk Factors ◽

De Novo ◽

Patient Age ◽

Patient Âgé ◽

Long Term Follow Up ◽

De Novo Aneurysm ◽

The Mean ◽

Risk Of Hemorrhage

Object A small percentage of patients will develop a completely new or de novo aneurysm after discovery of an initial aneurysm. The natural history of these lesions is unknown. The authors undertook this statistical evaluation a large cohort of patients with both ruptured and unruptured de novo aneurysms with the aim of analyzing risk factors for rupture and estimating a risk of subarachnoid hemorrhage (SAH). Methods A review of a prospectively maintained database of all aneurysm patients treated by the vascular neurosurgery service of Goodman Campbell Brain and Spine from 1976–2010 was performed. Of the 4718 patients, 611 (13%) had long-term follow-up imaging. The authors identified 27 patients (4.4%) with a total of 32 unruptured de novo aneurysms from routine surveillance imaging. They identified another 10 patients who presented with a new SAH from a de novo aneurysm after treatment of their original aneurysm. The total study group was thus 37 patients with a total of 42 de novo aneurysms. The authors then compared the 27 patients with incidentally discovered aneurysms with the 10 patients with SAH. A statistical analysis was performed, comparing the 2 groups with respect to patient and aneurysm characteristics and risk factors. Results Thirty-seven patients were identified as having true de novo aneurysms. This group had a female predominance and a high percentage of smokers. These 37 patients had a total of 42 de novo aneurysms. Ten of these 42 aneurysms hemorrhaged. De novo aneurysms in both the SAH and non-SAH group were anatomically small (< 10 mm). The estimated risk of hemorrhage over 5 years was 14.5%, higher than the expected SAH risk of small, unruptured aneurysms reported in the ISUIA (International Study of Unruptured Intracranial Aneurysms) trial. There was no statistically significant correlation between hemorrhage and any of the following risk factors: hypertension, diabetes, tobacco and alcohol use, polycystic kidney disease, or previous SAH. There was a statistically significant between-groups difference with respect to patient age, with the mean patient age being significantly older in the SAH aneurysm group than in the non-SAH group (p = 0.047). This is likely reflective of longer follow-up and discovery time, as the mean length of time between initial treatment and discovery of the de novo aneurysm was longer in the SAH group (p = 0.011). Conclusions While rare, de novo aneurysms may have a risk for SAH that is comparatively higher than the risk associated with similarly sized, small, initially discovered unruptured saccular aneurysms. The authors therefore recommend long-term follow-up for all patients with aneurysms, and they consider a more aggressive treatment strategy for de novo aneurysms than for incidentally discovered initial aneurysms.

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Risk factors for complications after endoscopic treatment in Chinese patients with early esophageal cancer and precancerous lesions

Surgical Endoscopy ◽

10.1007/s00464-020-07619-z ◽

2020 ◽

Author(s):

Xinying Yu ◽

Yong Liu ◽

Liyan Xue ◽

Shun He ◽

Yueming Zhang ◽

...

Keyword(s):

Risk Factors ◽

Esophageal Cancer ◽

Endoscopic Treatment ◽

Precancerous Lesions ◽

Chinese Patients ◽

Early Esophageal Cancer

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Outcomes of Kidney Transplant Tourism and Risk Factors for De Novo Urothelial Carcinoma

Transplantation Journal ◽

10.1097/tp.0000000000000023 ◽

2014 ◽

Vol 98 (1) ◽

pp. 79-87 ◽

Cited By ~ 12

Author(s):

Hsin-Lin Tsai ◽

Jei-Wen Chang ◽

Tsai-Hun Wu ◽

Kuang-Liang King ◽

Ling-Yu Yang ◽

...

Keyword(s):

Risk Factors ◽

Urothelial Carcinoma ◽

Kidney Transplant ◽

De Novo ◽

Transplant Tourism

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Su1417 Outcomes of Colorectal Endoscopic Submucosal Dissection and Risk Factors for Technical Difficulty: A Prospective Multi-Center Study on Endoscopic Treatment of Large Early Colorectal Neoplasms

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2012.03.842 ◽

2012 ◽

Vol 75 (4) ◽

pp. AB324-AB325 ◽

Cited By ~ 1

Author(s):

Yoji Takeuchi ◽

Yutaka Saito ◽

Hiroyasu Iishi ◽

Hiroaki Ikematsu ◽

Shin-Ei Kudo ◽

...

Keyword(s):

Risk Factors ◽

Endoscopic Submucosal Dissection ◽

Colorectal Neoplasms ◽

Endoscopic Treatment ◽

Technical Difficulty ◽

Submucosal Dissection ◽

Colorectal Endoscopic Submucosal Dissection ◽

Multi Center Study ◽

Center Study

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Risk factors impacting intra- and postoperative cerebrospinal fluid rhinorrhea on the endoscopic treatment of pituitary adenomas

Medicine ◽

10.1097/md.0000000000027781 ◽

2021 ◽

Vol 100 (49) ◽

pp. e27781

Author(s):

Ming Wang ◽

Yang Cai ◽

Yugang Jiang ◽

Yong Peng

Keyword(s):

Risk Factors ◽

Cerebrospinal Fluid ◽

Endoscopic Treatment ◽

Pituitary Adenomas ◽

Cerebrospinal Fluid Rhinorrhea

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Risk factors for anastomotic complications after one-stage anastomosis for oesophageal atresia

Journal of Cardiothoracic Surgery ◽

10.1186/s13019-021-01557-0 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Jin-Xi Huang ◽

Song-Ming Hong ◽

Qiang Chen ◽

Zeng-Chun Wang ◽

Dian-Ming Wu ◽

...

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Birth Weight ◽

Oesophageal Atresia ◽

Prognostic Nutritional Index ◽

Anastomotic Stenosis ◽

Multivariate Logistic Regression ◽

One Stage ◽

Nutritional Index ◽

Anastomotic Fistula

Abstract Background Oesophageal atresia is a congenital malformation of the oesophagus and a serious malformation of the digestive system, postoperative complications include acute respiratory failure, pneumonia, anastomotic fistula, anastomotic stenosis, tracheal stenosis, gastroesophageal reflux and eosinophilic oesophagitis, anastomotic fistula is one of the important causes of postoperative death. The objective of this study is to identify the risk factors for anastomotic complications after one-stage anastomosis for oesophageal atresia. Methods A retrospective analysis was performed on the clinical data of 107 children with congenital oesophageal atresia who underwent one-stage anastomosis in our hospital from January 2013 to December 2018. Single-factor and multivariate logistic regression analyses were performed to determine the risk factors for anastomotic fistula and anastomotic stenosis. Results A total of 107 children with oesophageal atresia underwent one-stage anastomosis, and the incidence of anastomotic fistula was 26.2%. The probability of anastomotic stenosis in the long term was 52.3%, and the incidence of refractory stenosis (dilation ≥5 times) was 13.1%. Analysis of the clinical count data in the anastomotic fistula group and non-anastomotic fistula group showed that preoperative albumin (F = 4.199, P = 0.043), low birth weight (F = 7.668, P = 0.007) and long gap defects (F = 6.107, P = 0.015) were risk factors for postoperative anastomotic fistula. Further multivariate logistic regression analysis showed that low birth weight (Wald2 = 4.499, P = 0.034, OR = 2.775) and long gap defects (Wald2 = 6.769, P = 0.009, OR = 4.939) were independent risk factors for postoperative anastomotic fistula. Premature delivery (F = 5.338, P = 0.023), anastomotic fistula (F = 11.381, P = 0.001), endoscopic surgery (F = 6.343, P = 0.013), preoperative neutrophil count (F = 8.602, P = 0.004), preoperative low albumin (F = 8.410, P = 0.005), and a preoperative prognostic nutritional index < 54 (F = 5.54, P = 0.02) were risk factors for refractory anastomotic stenosis in children. Further multivariate logistic regression analysis showed that postoperative anastomotic fistula (Wald2 = 11.417, P = 0.001, OR = 8.798), endoscopic surgery (Wald2 = 9.633, P = 0.002, OR = 4.808), and a prognostic nutritional index < 54 (Wald2 = 4.540, P = 0.002, OR = 2.3798) were independent risk factors for refractory anastomotic stenosis. Conclusion Low birth weight and long gap defects are important predictors of postoperative anastomotic fistula, and the possibility of refractory anastomotic stenosis should be considered. The long-term risk of anastomotic stenosis was increased in children undergoing endoscopic surgery and in those with a preoperative prognostic nutritional index < 54.

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