Retrograde intrarenal surgery and percutaneous nephrolithotomy: Infectious complications and risk factors in a prospective clinical study

Objective Stone disease is one of the most common afflictions in modern society. Complications following retrograde intrarenal surgery (RIRS) vary considerably, and small-diameter ureteral access sheaths are reportedly significantly associated with rates of infectious complications following RIRS. This study aimed to explore additional risk factors for infectious complications after RIRS. Methods This study retrospectively analyzed 602 patients who underwent RIRS between December 2016 and October 2019 at the First Affiliated Hospital of Fujian Medical University. All flexible ureteroscopic lithotripsy processes were conducted with patients under general anesthesia in the low lithotomy position. Postoperative systemic inflammatory response syndrome (SIRS) was diagnosed; statistical analyses comprised two-way analysis of variance (ANOVA) and one-way multivariate ANOVA. Results The incidence of infectious complications after RIRS was 7.14%. Operative time was an independent risk factor that increased the risk of infection. Stone size >2 cm was observed in 153 (27.37%) patients in the SIRS group and 29 patients (67.44%) in the non-SIRS group. Conclusions Findings in the literature suggest that early antibiotic treatment and active fluid therapy might lower the rate of infectious complications after RIRS. Our results indicate that extended operative time and increased stone size may be risk factors for infectious complications after RIRS.

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Risk factors for bronchiolitis: Presentation of an on-going prospective clinical study

Inflammation Research ◽

10.1007/s000110050099 ◽

1997 ◽

Vol 46 (0) ◽

pp. 85-86 ◽

Cited By ~ 2

Author(s):

M. E. M Thompson ◽

J. K. Nelson ◽

C. McMaster, M. C. Stewart, M. D. Shie

Keyword(s):

Risk Factors ◽

Clinical Study ◽

Prospective Clinical Study

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The Evaluation of Risk Factors for Postoperative Infectious Complications after Percutaneous Nephrolithotomy

BioMed Research International ◽

10.1155/2017/4832051 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 5

Author(s):

Tian Yang ◽

Shenghua Liu ◽

Jimeng Hu ◽

Lujia Wang ◽

Haowen Jiang

Keyword(s):

Risk Factors ◽

Serum Albumin ◽

Percutaneous Nephrolithotomy ◽

Protective Factor ◽

Clinical Information ◽

Renal Stones ◽

Infectious Complications ◽

Stone Size ◽

Postoperative Fever ◽

Detailed Clinical Information

This study was to evaluate the risk factors of infectious complications after percutaneous nephrolithotomy (PCNL) and build a prediction tool for postoperative complications based on the risk factors. A total of 110 male (67.1%) and 54 female (32.9%) patients who underwent PCNL for renal stones between 2010 and 2014 in our institute were included. A detailed clinical information and laboratory results were obtained from patients. Systemic inflammatory response syndrome (SIRS) and postoperative fever were recorded after PCNL surgery. In all, 45 cases (27.4%) developed SIRS and fever was observed in 20 cases (12.2%). In multivariate analysis, stone size (odds ratio, OR = 1.471,p=0.009) and urine white blood cell (WBC) (OR = 1.001,p=0.007) were related to the development of SIRS. Stone size (OR = 1.644,p=0.024), urine WBC (OR = 1.001,p=0.002) and serum albumin (OR = 0.807,p=0.021) were associated with postoperative fever. We concluded that patients with larger stone size and preoperative urinary tract infection might have a higher risk of developing SIRS and fever after operation, while a high-normal level of serum albumin might be the protective factor for postoperative fever.

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