P.06.8: High Yield of Core Tissue for Histological Analysis with High Diagnostic Accuracy of EUS-Fine Needle Biopsy Using the 22G Acquire™ Needle: A Multicenter Prospective Study

Introduction: Fine Needle Biopsy (FNB) has been suggested to provide better histological samples as compared to endoscopic ultrasound fine needle aspiration (EUS-FNA). However, studies comparing EUS-FNA and EUS-FNB for pancreatic lesions reported contrasting results. The aim of this study was to compare the clinical performance of EUS-FNA versus EUS-FNB with ProCore needle for the investigation of pancreatic lesions. Methods: We reviewed all patients undergoing EUS for the investigation of pancreatic lesions from August 2012 to September 2018. From August 2012 to January 2015 all procedures were performed with standard needles, whereas from February 2015 to September 2018 the use of ProCore needles had been introduced. Data on diagnostic accuracy, number of needle passes and/or adverse events were collected. Results: 324 patients were retrospectively evaluated: 190 (58.6%) underwent EUS-FNA and 134 (41.4%) EUS-FNB. Both EUS-FNA and EUS-FNB showed high diagnostic accuracy for malignancy [94% (CI 95%:89-97%) vs 94% (CI 95%:89-98%)]. Notable, there were no differences between EUS-FNA and EUS-FNB in terms of sensitivity, specificity, positive and negative likelihood ratio, histological core tissue retrieval, adverse events or number of needle passes. However, subgroup analysis noted a higher diagnostic accuracy for 25G EUS-FNB as compared to 25G EUS-FNA (85,7% vs 55,5%; *p=0.023). Conclusion: EUS-FNB with ProCore needle is safe and feasible in pancreatic lesions. ProCore needle did not provide any advantage in terms of diagnostic accuracy, sensitivity, specificity, positive and/or negative likelihood ratio, or acquisition of core specimen, therefore its routine application is not

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Mammographic Fine Needle Biopsy of Non-Palpable Breast Lesions

Acta Radiologica Diagnosis ◽

10.1177/028418518402500405 ◽

1984 ◽

Vol 25 (4) ◽

pp. 273-276 ◽

Cited By ~ 7

Author(s):

M. Kehler ◽

U. Albrechtsson

Keyword(s):

Diagnostic Accuracy ◽

Needle Biopsy ◽

Fine Needle Biopsy ◽

Breast Lesions ◽

Malignant Cells ◽

Fine Needle ◽

The Past ◽

Palpable Breast ◽

Short Time ◽

Observation Period

Results with a previously described device for fine needle biopsies of non-palpable breast lesions are reported. During the past 5 years 182 biopsies were performed and 133 of these yielded diagnostic cell material. In the series, 41 carcinomas were found and fine needle biopsy in all demonstrated malignant or probably malignant cells. In the biopsies evaluated as benign or probably benign, malignancy has not been found during the observation period of 4 to 59 months (mean 21.5 months). The device described is cheap and biopsy is easily performed and, if necessary, repeated in a short time. The diagnostic accuracy is high and carcinomas as small as 3 mm in diameter have been diagnosed.

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Su1297 ENDOSCOPIC ULTRASOUND-GUIDED FINE NEEDLE BIOPSY: DIAGNOSTIC ACCURACY OF CYTOLOGY AND HISTOLOGY

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2020.03.2143 ◽

2020 ◽

Vol 91 (6) ◽

pp. AB319

Author(s):

Liza Plafsky ◽

Tara Keihanian ◽

Jinendra L. Satiya ◽

Liege I. Diaz ◽

Mohit Girotra

Keyword(s):

Diagnostic Accuracy ◽

Endoscopic Ultrasound ◽

Needle Biopsy ◽

Fine Needle Biopsy ◽

Ultrasound Guided ◽

Fine Needle

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Diagnostic Accuracy of Fine-Needle Biopsy for Salivary Gland Neoplasms in a Community Otolaryngology Practice

OTO Open ◽

10.1177/2473974x20949184 ◽

2020 ◽

Vol 4 (3) ◽

pp. 2473974X2094918

Author(s):

Jennifer L. Harb ◽

Dara Bakar ◽

Jagdish K. Dhingra

Keyword(s):

Salivary Gland ◽

Parotid Gland ◽

Diagnostic Accuracy ◽

Submandibular Gland ◽

Sensitivity And Specificity ◽

Needle Biopsy ◽

Fine Needle Biopsy ◽

Salivary Gland Neoplasms ◽

Community Practice ◽

Fine Needle

Objective To assess the diagnostic accuracy of fine-needle biopsy (FNB) of salivary gland neoplasms via ultrasound (US) or palpation guidance by an otolaryngologist in a community practice. Study Design Retrospective chart review. Setting Community otolaryngology practice. Methods Retrospective analysis was conducted for all office-based salivary gland FNBs from a community practice from 2005 through 2018. There were 433 FNBs performed among 370 patients. The likelihood of achieving a diagnostic result based on method (US vs palpation guidance) was calculated. Of this cohort, 196 cases had surgical follow-up (parotid gland, n = 168; submandibular gland, n = 28). Correlation of preoperative FNB results to final surgical pathology was performed and measures of diagnostic accuracy computed. Results US-guided FNBs were more likely to achieve a diagnostic result than FNBs obtained via palpation guidance ( P = .00002). Parotid gland FNBs demonstrated a sensitivity and specificity of 78.57% and 92.44%, respectively. Submandibular FNBs demonstrated a sensitivity and specificity of 57.14% and 93.74%. Conclusion FNBs performed under US guidance are more likely to achieve a diagnostic specimen than those performed under palpation guidance. FNBs of parotid gland tumors may be assessed with diagnostic accuracy in the community setting that is similar to that achieved at tertiary care centers. Further research is needed to ascertain whether this finding extends to FNBs of submandibular gland tumors. Offering this procedure at point of care in the community may improve compliance and reduce wait time.

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