369 THE RELATIONSHIP OF PAIN SEVERITY TO CEREBRAL WHITE MATTER ABNORMALITIES IN PATIENTS WITH PRIMARY SJOGREN'S SYNDROME

2010 ◽  
Vol 4 (S1) ◽  
pp. 105-105
Author(s):  
B. Segal ◽  
B. Mueller ◽  
K. Lim
Keyword(s):  
White Matter ◽  
Sjogren's Syndrome ◽  
Primary Sjögren’S Syndrome ◽  
Pain Severity ◽  
Cerebral White Matter ◽  
Primary Sjogren’S Syndrome ◽  
Primary Sjögren's Syndrome ◽  
White Matter Abnormalities ◽  
Relationship Of ◽  
The Relationship

Primary Sjögren’s Syndrome White Matter Changes and Cognitive Dysfunction

2016 ◽  
Vol 46 (1) ◽  
pp. 27-33
Author(s):  
Mary Dess ◽  
Wayne F. Heidenreich
Keyword(s):  
White Matter ◽  
Sjögren’S Syndrome ◽  
Cognitive Dysfunction ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Primary Sjögren’S Syndrome ◽  
Primary Sjogren’S Syndrome ◽  
Primary Sjögren's Syndrome ◽  
Sjögren‘S Syndrome

This case report describes a 52-year-old, female applicant for long term-care insurance with a history of an autoimmune connective tissue disease initially diagnosed as systemic lupus erythematosus (SLE). Over several years, the signs and symptoms evolved into a clear diagnosis of primary Sjögren’s syndrome (PSS). The specific criteria for this diagnosis are reviewed including the symptoms, antinuclear antibodies (ANA), extractable nuclear antigen antibodies (ENA), abnormal salivary scintigraphy and positive Schirmer test. Symptoms of neuropathy and the possibility of a cognitive dysfunction are discussed as part of PSS. The association of white matter lesions (WML) with PSS is significant for underwriting consideration.

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