scholarly journals Gastrointestinal stromal tumors (GISTs): role of CD 117 and PDGFRA Golgi-like staining pattern in the recognition of mutational status

2012 ◽  
Vol 104 (3) ◽  
pp. 128-133 ◽  
Author(s):  
Sara Jaramillo ◽  
María José Ríos-Moreno ◽  
Alicia Hernández ◽  
Joaquín Amérigo ◽  
Inmaculada Trigo-Sánchez ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumors ◽  
Staining Pattern ◽  
Stromal Tumors ◽  
Cd 117 ◽  
Mutational Status

scholarly journals Clinical Overview of GIST and Its Latest Management by Endoscopic Resection in Upper GI: A Literature Review

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Cicilia Marcella ◽  
Rui Hua Shi ◽  
Shakeel Sarwar
Keyword(s):  
Endoscopic Resection ◽  
Gastrointestinal Stromal Tumors ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
Endoscopic Techniques ◽  
Stromal Tumors ◽  
Upper Gi ◽  
Risk Of Malignancy

Aims. To review the clinical presentation, diagnosis, assessment of risk of malignancy, and recent advances in management (mainly focusing on the role of endoscopic resection) of gastrointestinal stromal tumors (GISTs) in upper GI.Method. We searched Embase, Web of science, and PubMed databases from 1993 to 2018 by using the following keywords: “gastrointestinal stromal tumors,” “GIST,” “treatment,” and “diagnosis.” Additional papers were searched manually from references of the related articles.Findings. The improvement of endoscopic techniques in treating upper gastrointestinal subepithelial tumors especially gastrointestinal tumors has reduced the need for invasive surgery in patients unfit for surgery. Many studies have concluded that modified endoscopic treatments are effective and safe. These treatments permit minimal tissue resection, better dissection control, and high rates of en bloc resection with an acceptable rate of complications.

scholarly journals Role of PLK1 signaling pathway genes in gastrointestinal stromal tumors

2018 ◽  
Author(s):  
Jen‑Shi Chen ◽  
Chun‑Nan Yeh ◽  
Chi‑Tung Cheng ◽  
Chueh‑Chuan Yen ◽  
Yen‑Yang Chen ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Gastrointestinal Stromal Tumors ◽  
Stromal Tumors

scholarly journals The role of FBXW7, a cell-cycle regulator, as a predictive marker of recurrence of gastrointestinal stromal tumors

2019 ◽  
Vol 22 (6) ◽  
pp. 1100-1108
Author(s):  
Yuki Koga ◽  
Masaaki Iwatsuki ◽  
Kohei Yamashita ◽  
Yuki Kiyozumi ◽  
Junji Kurashige ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Gastrointestinal Stromal Tumors ◽  
Predictive Marker ◽  
Stromal Tumors ◽  
Cell Cycle Regulator ◽  
A Cell

Abstract 08: Role of upfront genomic analysis of gastrointestinal stromal tumors to identify imatinib-insensitive or resistant cases

2016 ◽  
Author(s):  
Aleksander Chojecki ◽  
Rebecca A. Moss ◽  
Hua Zhong ◽  
Elizabeth Poplin ◽  
Ellen Ronnen ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumors ◽  
Genomic Analysis ◽  
Stromal Tumors

scholarly journals A Malignant Gastrointestinal Stromal Tumor of the Gallbladder Immunoreactive for PDGFRA and Negative for CD 117 Antigen (c-KIT)

HPB Surgery ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Athanasios Petrou ◽  
Pari Alexandrou ◽  
Alexandros Papalambros ◽  
Angelica Saetta ◽  
Paraskevi Fragkou ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Growth Factor Receptor ◽  
Stromal Tumor ◽  
Platelet Derived Growth Factor ◽  
Stromal Tumors ◽  
Cd 117 ◽  
Factor Receptor Alpha ◽  
Malignant Gists ◽  
First Time

Gastrointestinal stromal tumors (GISTs) compose the largest category of well-recognized nonepithelial neoplasms of the gastrointestinal tract (GI). GISTs of the gallbladder are extremely rare tumors. Only four malignant, two benign and one GIST-like tumor of the gall bladder have ever been described. The four malignant GISTs were all positive for CD 117 antigen (c-kit). We present for the first time a malignant gastrointestinal stromal tumor of the gallbladder, immunoreactive for platelet-derived growth factor receptor alpha (PDGFRA) and negative for CD 117 antigen (c-KIT).

scholarly journals Role of surgery in patients with focally progressive gastrointestinal stromal tumors resistant to imatinib

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Xiaodong Gao ◽  
Anwei Xue ◽  
Yong Fang ◽  
Ping Shu ◽  
Jiaqian Ling ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumors ◽  
Stromal Tumors

scholarly journals Extragastrointestinal Stromal Tumor during Pregnacy

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Ilay Gözükara ◽  
T. U. Kutlu Dilek ◽  
Hüseyin Durukan ◽  
Duygu Düsmez Apa ◽  
Suna Kabil Kucur ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Stromal Tumors ◽  
Stromal Tumor ◽  
Stromal Tumors ◽  
Cd 117 ◽  
Extragastrointestinal Stromal Tumor ◽  
Mesenchymal Neoplasms ◽  
Oncogene Protein

Extragastrointestinal stromal tumors (EGISTs) are mesenchymal neoplasms without connection to the gastrointestinal tract. Gastrointestinal stromal tumors (GISTs) and EGIST are similar according to their clinicopathologic and histomorphologic features. Both of them most often express immunoreactivity for CD-117, a c-kit proto-oncogene protein. The coexistence of GIST and pregnancy is very rare, with only two cases reported in the literature. In this paper, we presented the first EGIST case during pregnancy in the literature.

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