scholarly journals P.115 Vessel Wall Imaging of Unusual Childhood Strokes: a Pediatric Case Series

Author(s):  
FF Albassam ◽  
P Muthusami ◽  
N Dlamini

Background: MR-based vessel wall imaging (VWI) has gained influence in the clinical investigations, and management of pediatric strokes. Limitations still exist in interpreting it as a singular modality. Methods: We present 4 pediatric stroke cases with VWI enhancement. Results: Case 1. 4-year old boy with sickle cell anemia, who developed encephalopathy during a hemolytic crisis. MR-VWI revealed bilateral extracranial internal carotid enhanced narrowing, deemed a secondary vasculopathy, with resolution upon follow-up. Case 2. 16-year old male presented with left middle cerebral artery (MCA) infarction. VWI revealed left internal carotid terminus and proximal MCA enhancement. Conventional angiography showed abnormalities in mesentric and hepatic arteries. Stability sustained on anticoagulation and immunosuppressive therapy. Case 3. 10-year old girl, developed bilateral MCA infarctions with enhanced extracranial segments of both ICAs, and narrow PCAs, consistent with Moyamoya vasculopathy. Improved on combined immunosuppressive and anticoagulation therapy. Case 4. 13-year old boy had an episode of right facial weakness, with a normal neurological exam; with enhancement and narrowing in the left extracranial ICA, likely an intramural hematoma from dissection. He responded to dual anticoagulation therapy. Conclusions: In conclusion, these cases illustrate similarities in vessel wall imaging abnormalities under different clinical contexts, with practical utility in longitudinal follow-up and prognostication.

2011 ◽  
Vol 33 (2) ◽  
pp. 230-237 ◽  
Author(s):  
N. Bianda ◽  
M. Di Valentino ◽  
D. Periat ◽  
J. M. Segatto ◽  
M. Oberson ◽  
...  

2020 ◽  
pp. 32-34
Author(s):  
Matheus Kahakura Franco Pedro ◽  
Paulo Sérgio Faro Santos ◽  
Bruno Augusto Telles

Reversible Cerebral Vasoconstriction Syndrome (RCVS) is a clinical and radiological syndrome that is primarily defined by thunderclap headache, with or without further neurological deficits, and segmental intracranial vasoconstriction that resolves within three months. The current nomenclature was only established in 2007, but it has been known with diferent names for over fifty years. The pathophysiology, while still not completely understood, seems to point towards a disease based on abnormalities of vascular tonus without structural inflammation. It is clear, however, that patients with RCVS often have triggers, especially drugs or other vasoactive substances. Distinguishing this entity from others, especially subarachnoid hemorrhage and arterialdissection, is extremely important, given the particular prognosis and need of immediate treatment of each disease. The preferred imaging method has long been the angiography; however, new magnetic resonance imaging (MRI) such as vessel wall imaging have allowed for non-invasivediagnosis and follow-up. The authors report a case in which MRI was used in a patient with basilar artery RCVS and present a literature review.


2019 ◽  
Author(s):  
Yao Yu ◽  
Hong-Wei Zhou ◽  
Zhen-Ni Guo ◽  
Hang Jin ◽  
Fu-Liang Zhang ◽  
...  

Abstract Background Primary angiitis of the central nervous system is an uncommon single-organ vasculitis that is still poorly understood, and its diagnosis can be quite challenging. Traditional vascular imaging techniques could only show the abnormality of vessel lumen, while primary angiitis of the central nervous system as well as atherosclerosis or other mimics could show similar patterns, like tapering of the vessel lumen or multiple stenosis. Vessel wall magnetic resonance imaging can directly visualize the abnormality of the vessel wall, therefore has become a valuable approach for vasculopathy evaluation. However, 2D vessel wall magnetic resonance imaging can only be restricted to one fixed angle for one scanning process, while vasculitis tends to involve multiple vessels. With the development of 3D isotropic vessel wall imaging sequence, it can achieve a thorough view of the whole brain vasculature in shorter time and apply reconstruction in any angle. Reasonably, 3D isotropic vessel wall imaging could help with the diagnosis, evaluation and follow-up of primary angiitis of the central nervous system more effectively. Case presentation We present five cases of primary angiitis of the central nervous system that underwent 3D isotropic vessel wall imaging, along with follow-up. The diagnosis of primary angiitis of the central nervous system was made by classic diagnosis criteria. The youngest patient was 21 years old, while the oldest one was 49 years old. As for disease onset, one patient presented with headache, while other four patients presented with ischemic stroke. Both anterior circulation and posterior circulation of the five patients were involved, regardless of the responsible vessel. They were given steroids, immunosuppressor or parahormone for management. On follow-up vessel imaging, one patient displayed gradual vessel occlusion in 12 months, one patient showed partial resolution, other three patients presented with vasculopathy persistence. Conclusions 3D isotropic vessel wall imaging could evaluate the specific responsible vessel as well as the whole brain vasculature in one-time scan, providing detailed information in detection, diagnosis, evaluation and follow-up. Moreover, primary angiitis of the central nervous system tend to be multi-vessel involving, so the 3D isotropic vessel wall imaging could be more applicable.


Author(s):  
Yukishige Hashimoto ◽  
Toshinori Matsushige ◽  
Koji Shimonaga ◽  
Michitsura Yoshiyama ◽  
Hiroki Takahashi ◽  
...  

2020 ◽  
Vol 78 (10) ◽  
pp. 642-650
Author(s):  
Felipe Torres PACHECO ◽  
Luiz Celso Hygino da CRUZ JUNIOR ◽  
Igor Gomes PADILHA ◽  
Renato Hoffmann NUNES ◽  
Antônio Carlos Martins MAIA JUNIOR ◽  
...  

ABSTRACT Intracranial vessel wall imaging plays an increasing role in diagnosing intracranial vascular diseases. With the growing demand and subsequent increased use of this technique in clinical practice, radiologists and neurologists should be aware of the choices in imaging parameters and how they affect image quality, clinical indications, methods of assessment, and limitations in the interpretation of these images. Due to the improvement of the MRI techniques, the possibility of accurate and direct evaluation of the abnormalities in the arterial vascular wall (vessel wall imaging) has evolved, adding substantial data to diagnosis when compared to the indirect evaluation based on conventional flow analyses. Herein, the authors proposed a comprehensive approach of this technique reinforcing appropriated clinical settings to better use intracranial vessel wall imaging.


2021 ◽  
Author(s):  
Neha Choudhary ◽  
Sameer Vyas ◽  
Manish Modi ◽  
Shashank Raj ◽  
Ajay Kumar ◽  
...  

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