scholarly journals P.199 Variability descriptors of cerebral blood flow velocity as predictors of vasospasm in Subarachnoid Hemorrhage: A feasibility study

2021 ◽  
Vol 48 (s3) ◽  
pp. S77-S77
Author(s):  
RA Rodriguez ◽  
C Herry ◽  
S English ◽  
T Ramsay ◽  
A Seely ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Subarachnoid Hemorrhage ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
High Frequency ◽  
Cerebral Blood Flow Velocity ◽  
Spectral Power ◽  
Healthy Controls ◽  
Frequency Power

Background: Transcranial Doppler (TCD) measurements poorly predict vasospasm in patients with aneurysmal subarachnoid hemorrhage (aSAH). Variability descriptors of mean cerebral blood flow velocity (mean-CBFV) may improve this prediction. We assessed the feasibility of generating reliable mean-CBFV variability metrics using extended TCD recordings in aSAH patients and healthy controls. We also explored whether these parameters are capable to discriminate aSAH patients from healthy controls, and between patients with and without vasospasm. Methods: Bilateral mean-CBFV, systemic blood pressure and heart rate were recorded for 40 minutes in 3 groups: aSAH patients (n=8) within the first 5 days post-ictus, age-matched healthy controls (n=8) and young healthy controls (n=8). We obtained linear [standard deviations, coefficient of variations, very-low, low and high-frequency power-spectra] and non-linear [Fractality, deterministic Chaos analyses] variability metrics. Results: All TCD recordings provided consistent variability metrics. aSAH patients showed higher correlation dimensions, increased high-frequency spectral power, and decreased very-low frequency power than healthy controls. aSAH patients who developed vasospasm (n=3) showed higher mean-CBFV and lower coefficient of variations than those without vasospasm (n=5). Conclusions: Descriptors of mean-CBFV variability may distinguish between aSAH patients with and without vasospasm. Future studies are required to evaluate the role of these variability parameters for risk stratification in aSAH.

Biphasic Cerebral Blood Flow Velocity Profile in Patients With Aneurysmal Subarachnoid Hemorrhage

2004 ◽  
Vol 1 (4) ◽  
pp. 455-460 ◽  
Author(s):  
Andreas R. Luft ◽  
Manuel M. Buitrago ◽  
Michel Torbey ◽  
Anish Bhardwaj ◽  
Alexander Razumovsky
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Subarachnoid Hemorrhage ◽  
Velocity Profile ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Flow Velocity Profile

Abstract TP421: Cerebral Blood Flow Dynamics and Head-of-Bed Changes in the Setting of Subarachnoid Hemorrhage

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
David K Kung ◽  
Nohra Chalouhi ◽  
Pascal M Jabbour ◽  
Aaron S Dumont ◽  
H. R Winn ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Subarachnoid Hemorrhage ◽  
Flow Velocity ◽  
Thermal Diffusion ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Regional Blood Flow ◽  
Cerebral Hypoperfusion ◽  
Sitting Position

Background: Head-of-bed (HOB) elevation is usually restricted in patients with aneurysmal subarachnoid hemorrhage (SAH). This practice is believed to prevent cerebral hypoperfusion. Objective: The goal of this study is to correlate HOB changes (0 o and 90 o ) with cerebral blood flow using Trans-cranial Doppler (TCD) and thermal diffusion probe in SAH patients. Methods: Thirteen patients with SAH were prospectively enrolled in the study. Eight patients underwent placement of a thermal diffusion probe for regional CBF measurement in the same setting when placing a ventriculostomy. CBF values were measured by TCD alone (13 subjects) or concurrently with thermal diffusion probe (8 subjects) with the patients in a flat (0 o ) and upright sitting position (90 o ) at day 3, 7, and 10. Results: The average increase in blood flow velocity when changing HOB from 0 o to 90 o was 7.8% on day 3, 0.1% on day 7, and 13.1% on day 10. The middle cerebral artery had the least changes in velocity compared to the anterior cerebral and the posterior cerebral arteries. The average regional CBF measurement was 22.7 +/- 10.3 ml/100g/min in the supine position and 23.6 +/- 9.1 mg/100g/min in the sitting position. The changes were not statistically significant. No change in clinical exam was appreciated. None of the patients developed clinical cerebral vasospasm. Conclusion: Changing HOB position in the setting of SAH did not significantly affect either cerebral blood flow velocity or regional blood flow. This data suggests that early mobilization should be considered given the detrimental effects of prolonged bed rest.

scholarly journals Effect of Age on Cerebral Blood Flow Velocity and Incidence of Vasospasm After Aneurysmal Subarachnoid Hemorrhage

Stroke ◽  
2001 ◽  
Vol 32 (9) ◽  
pp. 2005-2011 ◽  
Author(s):  
Michel T. Torbey ◽  
Till-Karsten Hauser ◽  
Anish Bhardwaj ◽  
Michael A. Williams ◽  
John A. Ulatowski ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Subarachnoid Hemorrhage ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Effect Of Age

Coupling between Visual Evoked Cerebral Blood Flow Velocity Responses and Visual Evoked Potentials in Migraneurs

Cephalalgia ◽  
2005 ◽  
Vol 25 (8) ◽  
pp. 567-574 ◽  
Author(s):  
M Zaletel ◽  
M Strucl ◽  
FF Bajrovi ◽  
T Pogacnik
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Evoked Potentials ◽  
Flow Velocity ◽  
Visual Evoked Potentials ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Neurovascular Coupling ◽  
Healthy Controls ◽  
Visual Evoked

Neurovascular coupling may be altered in migraneurs. Therefore, visual evoked potentials (VEP) and visually evoked cerebral blood flow velocity responses (VEFR) were simultaneously recorded in 30 healthy controls and 30 migraneurs interictally using a checkerboard stimulus with visual contrasts of 1%, 10% and 100%. The VEFR were measured in the posterior cerebral artery using transcranial Doppler and VEP were recorded from occipital leads. We found an increase in VEFR and VEP in both the healthy and migraneur groups ( P < 0.01). VEFR were significantly higher in migraneurs ( P < 0.01), while VEP did not significantly differ between the groups ( P > 0.05). Regression showed a significant association between VEP and VEFR in both healthy controls ( r = 0.66, P < 0.01) and migraneurs ( r = 0.63, P < 0.01). The regression coefficient of migraneurs (b = 0.88, SE = 0.08) was significantly higher than that of healthy controls (b = 0.55, SE = 0.07) ( P = 0.04). We conclude that neurovascular coupling is increased in migraneurs interictally.

Sign in / Sign up

Export Citation Format

Share Document