Extra-pulmonary small cell carcinoma of the neopharynx: case report and review of neopharyngeal tumours after total laryngectomy

2009 ◽  
Vol 124 (2) ◽  
pp. 216-219 ◽  
Author(s):  
A George ◽  
H Uppal ◽  
C Phelan ◽  
R Hughes

AbstractObjective:We report the first documented case in the world literature of primary extra-pulmonary small cell carcinoma occurring in the neopharynx following laryngectomy.Method:We present a case report and a review of the world literature regarding the management of tumours of the neopharynx and extra-pulmonary small cell carcinoma.Results:The paucity of cases of extra-pulmonary small cell carcinoma has resulted in many departments managing this neoplasm similarly to pulmonary small cell cancer. However, the site of the primary can have an impact on disease survival and treatment options.Conclusion:Neopharyngeal small cell carcinoma has not previously been reported. It should be managed in the same way as other extra-pulmonary small cell carcinomas occurring within the pharynx or larynx, with combined multi-drug chemotherapy and radiotherapy. Surgery has a limited role due to the aggressiveness of the disease and the high risk of local and distant spread at presentation.

2006 ◽  
Vol 55 (5) ◽  
pp. 477
Author(s):  
In Jae Lee ◽  
Kwang Seok Eom ◽  
Seon Young Jeon ◽  
Im Kyung Hwang ◽  
Yul Lee ◽  
...  

Pathology ◽  
2017 ◽  
Vol 49 ◽  
pp. S89
Author(s):  
Sagarika Tripathy ◽  
Anthony Kelmann

2008 ◽  
Vol 94 (3) ◽  
pp. 434-436 ◽  
Author(s):  
Marcello Tiseo ◽  
Elena Spiritelli ◽  
Marzia Capelletti ◽  
Guido Rindi ◽  
Andrea Ardizzoni

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Mutahir A. Tunio ◽  
Mushabbab AlAsiri ◽  
Asma Mohammed F. Ali ◽  
Eyad Fawzi AlSaeed ◽  
Muhammad Shuja ◽  
...  

Background. Small cell carcinoma (SCC) of the gallbladder is a rare entity and is often seen in elderly women. SCC of gallbladder is typically a nonsecretory carcinoid tumor without overt clinical symptoms and is often discovered at advanced stages. SCC of gallbladder carries a dismal prognosis as compared to SCC of lung and adenocarcinoma of gallbladder. To date, only 73 case reports have been published in the world literature.Case Presentation. Herein, we report a case of a 73-year-old Saudi woman who presented with one week history of right upper quadrant abdominal pain and obstructive jaundice and was found to be a case of locally advanced, metastatic SCC of gallbladder cT4N1M1 (liver, para-aortic lymph nodes, and bone). The patient was treated with neoadjuvant etoposide and cisplatin (EP) chemotherapy three cycles after biliary stenting followed by radical cholecystectomy, lymphadenectomy, and adjuvant EP chemotherapy and then one year later developed distal humerus osseous metastasis.Conclusion. SCC of the gallbladder is very rare entity and is often seen at advanced stages. Osseous metastases of peripheral skeleton from SCC gallbladder are rarely reported. Surgery is curative option but only for early stage tumors. Incorporation of chemotherapy along with radical resection increases the survival.


Onkologie ◽  
2013 ◽  
Vol 36 (7-8) ◽  
pp. 4-4 ◽  
Author(s):  
Sheng Zhang ◽  
Qian Cai ◽  
Li Fan ◽  
Ruiguang Zhang ◽  
Yingchao Zhao ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document