Role of neck dissection for metastatic nonseminomatous testicular carcinoma: case report and literature review

2013 ◽  
Vol 127 (10) ◽  
pp. 1038-1039 ◽  
Author(s):  
A O'Connor ◽  
A Dias ◽  
C Timon

AbstractObjectives:To review the incidence, treatment and prognosis of testicular carcinoma metastatic to the neck, and to propose a selective neck dissection be performed for residual disease post-chemotherapy.Case report:A 17-year-old young man with metastatic testicular carcinoma presented with a left neck mass. A palpable neck mass is the initial sign in approximately 5 per cent of cases of metastatic testicular teratoma. Approximately 30 per cent of patients with advanced-stage testicular cancer have extra-retroperitoneal disease post-chemotherapy, which requires resection. The presented patient underwent a left selective neck dissection, thymectomy, median sternotomy, left thoracotomy and mediastinal lymph node dissection. Eighteen months later, a computed tomography scan of the thorax showed no evidence of disease recurrence in the neck or mediastinum.Conclusion:While surgical management of testicular cancer retroperitoneal metastases is well described, there is limited literature on the management of cervical lymph node metastases. In the presented case of metastatic testicular carcinoma with cervical lymph node metastases, a selective neck dissection was successfully performed for a post-chemotherapy mass.

Head & Neck ◽  
2002 ◽  
Vol 24 (7) ◽  
pp. 678-683 ◽  
Author(s):  
Peter J. J. Gooris ◽  
Albert Vermey ◽  
Jan G. A. M. de Visscher ◽  
Fred R. Burlage ◽  
Jan L. N. Roodenburg

Medicina ◽  
2020 ◽  
Vol 56 (7) ◽  
pp. 343
Author(s):  
Shogo Shinohara ◽  
Hiroyuki Harada ◽  
Masahiro Kikuchi ◽  
Shinji Takebayashi ◽  
Kiyomi Hamaguchi

Background and Objectives: Patients with cervical lymph node metastases from remote primary tumours have poor prognoses because of the advanced stage of their cancer. Owing to recent progress in the nonsurgical management of various cancer types, options for surgical treatment to reduce tumour volume are increasing, and may help improve survival rates. For example, neck dissection may be a good option as a definitive therapy for some patients with resectable cervical metastases. We assessed patients who underwent neck dissection with curative intent and discuss the effectiveness of this approach for cervical metastases from remote malignancies. Material and Methods: We retrospectively reviewed the data of 18 patients (10 males and 8 females in an age range of 30–79 years) who underwent neck dissections for neck lymph node metastases from a remote primary tumour between 2010 and 2019. Patient clinical characteristics, preoperative accuracy of positive node localisation using fluorodeoxyglucose positron emission tomography–computed tomography (FDG/PET-CT), and patient survival rates were estimated. Results: Primary sites included ten lungs, two mammary glands, one thymus, one thoracic oesophagus, one stomach, one uterine cervix, one ovary, and one testis per patient. There were 19 levels with FDG/PET-CT positive nodes in 17 out of 18 patients. Conversely, there were 28 pathological positive levels out of 50 dissected levels. The sensitivity, specificity, positive and negative predictive values, and accuracy of FDG-PET/CT in predicting positive nodes were 69%, 88%, 95%, 47%, and 74%, respectively. The three-year overall survival (OS) rate for all patients was 70%. The three-year OS rate of the group with zero or one pathological positive nodes was 81%, which was significantly higher than that of the group with more than two positive nodes (51%) (p = 0.03). Conclusions: Neck dissection for cervical lymph node metastases from remote primary malignancies may improve prognoses, especially considering anticancer agents and radiotherapy advancements.


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