scholarly journals Positional Vertigo and Nystagmus of Central Origin

Author(s):  
P. Watson ◽  
H.O. Barber ◽  
J. Deck ◽  
K. Terbrugge

SUMMARY:Four cases are described illustrating the clinical features of positional vertigo and nystagmus due to posterior fossa tumors and a case of obstructive hydrocephalus. In these cases positional vertigo was the first and only presenting symptom of central nervous system disease. One case of subependymoma of the fourth ventricle and one with hydrocephalus had characteristic symptoms of benign positional vertigo; each showed positional nystagmus of the benign paroxysmal type.

2008 ◽  
Vol 19 (03) ◽  
pp. 257-266 ◽  
Author(s):  
David A. Zapala

Down-beating positional nystagmus is typically associated with central nervous system disease. Anterior canal benign paroxysmal positional vertigo (AC-BPPV) can mimic down-beating positional nystagmus of central origin, particularly when it is bilateral. Factors that increase the probability of bilateral AC-BPPV include a history of bilateral multicanal BPPV, transient down-beating and torsional nystagmus that follows the plane of the provoked canal, and the absence of co-occurring neurologic signs and symptoms of central nervous system dysfunction. With neurologic clearance for canalith repositioning, exploration for AC-BPPV and canalith repositioning trials may alleviate symptoms even when the nystagmus does not appear to fatigue. In the case presented, the use of a side-lying maneuver with the nose down to provoke AC-BPPV symptoms and the use of a reversed Epley to clear AC-BPPV symptoms are highlighted. This approach is helpful when the diagnosis is unclear and neck hyperextension is to be avoided. El nistagmo posicional de batida hacia abajo está típicamente asociado con enfermedades del sistema nervioso central. El vértigo posicional paroxístico benigno del canal anterior (AC-BPPV) puede simular un nistagmo posicional de batida hacia abajo de origen central, particularmente cuando es bilateral. Los factores que influyen sobre la probabilidad de un AC-BPPV bilateral incluyen una historia de BPPV multicanal bilateral, de nistagmo transitorio de batida hacia abajo o de nistagmo de torsión, que sigue el plano del canal provocado, y la ausencia de signos y síntomas neurológicos concurrentes por una disfunción del sistema nervioso central. Con una depuración neurológica de reposición canalicular, la exploración buscando AC-BPPV y los intentos de reposicionamiento canalicular pueden aliviar los síntomas aún cuando el nistagmo no parezca fatigarse. En el caso presentado, se destaca el uso de la maniobra de decúbito lateral con descenso de la nariz para provocar los síntomas del AC-BPPV. Este enfoque es útil cuando el diagnóstico no es claro y se debe evitar la hiperextensión del cuello.


2016 ◽  
Vol 65 (35) ◽  
pp. 930-933 ◽  
Author(s):  
Anita D. Sircar ◽  
Francisca Abanyie ◽  
Dean Blumberg ◽  
Peter Chin-Hong ◽  
Katrina S. Coulter ◽  
...  

2020 ◽  
Vol 60 (1) ◽  
pp. 291-309 ◽  
Author(s):  
Jesse A. Stokum ◽  
Volodymyr Gerzanich ◽  
Kevin N. Sheth ◽  
W. Taylor Kimberly ◽  
J. Marc Simard

Cerebral edema, a common and often fatal companion to most forms of acute central nervous system disease, has been recognized since the time of ancient Egypt. Unfortunately, our therapeutic armamentarium remains limited, in part due to historic limitations in our understanding of cerebral edema pathophysiology. Recent advancements have led to a number of clinical trials for novel therapeutics that could fundamentally alter the treatment of cerebral edema. In this review, we discuss these agents, their targets, and the data supporting their use, with a focus on agents that have progressed to clinical trials.


2021 ◽  
Vol 432 ◽  
pp. 213751
Author(s):  
Ke Chen ◽  
Si Sun ◽  
Junying Wang ◽  
Xiao-Dong Zhang

2019 ◽  
Vol 59 (5) ◽  
pp. E33-E37
Author(s):  
Stefano C. Previtali ◽  
Marina Scarlato ◽  
Paolo Vezzulli ◽  
Alessandra Ruggieri ◽  
Daniele Velardo ◽  
...  

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