The Ultrastructure of the Human Bronchial Submucosa

Author(s):  
G. L. Brinkman ◽  
N. Brooks ◽  
V. Bryant

Up until now the only clinical interest in the human submucosa has centered around the hypertrophy of the mucous secreting glands in patients with chronic cough and sputum. Besides this function, the submucosa, which is a loose connective tissue, provides mechanical and functional support for the mucosa and also contains numerous cells whose contribution to bronchial physiology is not yet fully understood.The mucosa is separated from the submucosa by the basement membrane, which is a thin, amorphous sheet between these two tissues. Auerbach has reported budding of the mucosal cells into the basement membrane in cigarette smoking dogs; a similar finding is shown in Figure 1 in a human cigarette smoker. Immediately beneath the basement membrane is a collection of reticular fibers which vary from being a thin layer of light density to a dense, thick layer of fibers. The reticular fibers are smaller, shorter and thinner than collagen fibers, and always single.

2009 ◽  
Vol 2 (3) ◽  
pp. 161-164 ◽  
Author(s):  
Ebrahim Rajabi ◽  
Abolghasem Nabipour

The histology of the oesophagus and crop was studied in six species of birds: Rock Dove, Collared Dove, Rose-ringed Parakeet, Kestrel, House Sparrow and Linnet. In species, the epithelium of oesophagus and crop was a keratinised stratified squamous. The lamina propria was a loose connective tissue containing glands. Glands were either purely mucous or seromucous (mixed). In the rock dove, rose-ringed parakeet and collared dove, there were no glands either in the cervical part of oesophagus or in the crop. There were differences in the histochemistry of glands’ secretions. The muscularis mucosa was present as a thick layer of smooth muscle fibres. The tunica submucosa was a loose connective tissue containing vessels and nerves. The tunica muscularis consisted of smooth muscle and was surrounded by the tunica adventitia at the cervical part of the oesophagus and crop, and by the tunica serosa at the thoracic part of the oesophagus.


The Angler ( Lophius piscatorius ) is a fish much modified for a bottom habit, and apart from many peculiarities of form and structure associated with this particular mode of life, is remarkable for the looseness of its skin and the abundance of soft connective tissue that separates it from the underlying fascia and muscles. Within this layer of loose connective tissue lie many of the larger trunks of the lymphatic system, mostly of very considerable size and easy to inject. The fish thus furnishes material better than most for the study of this system.


2007 ◽  
Vol 32 (5) ◽  
pp. 556-559 ◽  
Author(s):  
M. C. SBERNARDORI ◽  
P. BANDIERA

The histopathology of the central parts of 40 A1 pulleys from adult patients with primary trigger fingers was studied using light and transmission electron microscopes and the findings were compared with those in a control series of 10 normal A1 pulleys. The evaluation of the normal A1 pulley revealed a bi-laminar structure. The deepest layer was composed of dense normal connective tissue. The outermost layer was formed by loose connective tissue. In trigger digits, it was possible to identify a tri-laminar structure. The deepest layer was composed of irregular connective tissue, formed by small collagen fibres and abundant extracellular matrix. A considerable amount of chondroid-metaplasia was present in this layer. The middle layer contained dense, normal connective tissue with some fibrocytes. The outermost layer was formed of loose connective tissue. In conclusion, there was an additional layer in the A1 pulley in pathological cases which was not present in normal pulleys.


Author(s):  
Ping-An Wu ◽  
Ching-Hui Loh ◽  
Ling-Ling Hsieh ◽  
Tsung-Yun Liu ◽  
Chien-Jen Chen ◽  
...  

1975 ◽  
Vol 142 (1) ◽  
pp. 41-49 ◽  
Author(s):  
E Linder ◽  
A Vaheri ◽  
E Ruoslahti ◽  
J Wartiovaara

Fibroblast surface (SE) antigen is present in fibrillar surface structures of cultured normal fibroblasts, shed to the extracellular medium, and is also found in circulation (serum and plasma). Malignant fibroblasts (transformed by viruses) do not express SF antigen on the cell surface. In this study the in vivo differentiation and distribution of SF antigen has been investigated in the developing chick embryo using cryostat sections and immunofluorescence. The major findings were: (a) SF antigen was detectable in the loose connective tissue of very early (2-to 3-day old) embryos. (b) Condensation of SF antigen was seen in various boundary membranes such as the glomerular and tubular basement membranes of the kidney, the boundary membranes of the notochord, yolk sac, and vitelline membranes and liver sinusoids. (c) SF antigen was found to be cell-type specific. It was seen as a fibrillar network in the loose connective tissue of different organs but not in the parenchymal cells. It was not found in muscle cells at any stage of development. (d) The antigen was present in the undifferentiated mesenchymal cells of the kidney; but not found after their development into epithelial cells of the secretory tubules. (e) Both in vivo and in fibroblast cultures SF antigen was distributed as a fibrillar network. These data indicate that SF antigen is a "differentiation antigen" restricted to certain cells of mesenchymal origin and character, and that is accumulates in the connective tissue during embryogenesis.


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