Intracytoplasmic sperm injection – an update

2001 ◽  
Vol 9 (2) ◽  
pp. 141-151
Author(s):  
V Vernaeve ◽  
H Tournaye ◽  
P Devroey ◽  
A van Steirteghem

Infertility, a failure of conception after at least 12 months of unprotected intercourse, will affect 14–17% of couples at some time in their reproductive lives. The types of infertility, with their respective frequencies, are tubal and pelvic pathology (35%), male problems (35%), anovulation (15%), unexplained infertility (10%) and other infrequent problems (5%). While anovulation, mild/moderate endometriosis, unexplained infertility and moderate oligozoospermia can be treated with mild ovarian stimulation and timed intercourse and/or intrauterine insemination (IUI), no treatment options are available for nonoperable tubal problems or treatment failures with IUI.

2020 ◽  
Vol 38 (01) ◽  
pp. 048-054
Author(s):  
Rui Wang ◽  
Rik van Eekelen ◽  
Monique H. Mochtar ◽  
Femke Mol ◽  
Madelon van Wely

AbstractUnexplained infertility is a common diagnosis among couples with infertility. Pragmatic treatment options in these couples are directed at trying to improve chances to conceive, and consequently intrauterine insemination (IUI) with ovarian stimulation and in vitro fertilization (IVF) are standard clinical practice, while expectant management remains an important alternative. While evidence on IVF or IUI with ovarian stimulation versus expectant management was inconclusive, these interventions seem more effective in couples with a poor prognosis of natural conception. Strategies such as strict cancellation criteria and single-embryo transfer aim to reduce multiple pregnancies without compromising cumulative live birth. We propose a prognosis-based approach to manage couples with unexplained infertility so as to expose less couples to unnecessary interventions and less mothers and children to the potential adverse effects of ovarian stimulation or laboratory procedures.


2017 ◽  
Vol 20 (3) ◽  
pp. 200-203 ◽  
Author(s):  
Arie Berkovitz ◽  
Tal Biron-Shental ◽  
Yael Pasternak ◽  
Reuven Sharony ◽  
Anat Hershko-Klement ◽  
...  

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