Adenylyl Cyclase Activity and Mood Disorders: Preliminary Data in Human Brain Postmortem

CNS Spectrums ◽  
1998 ◽  
Vol 3 (10) ◽  
pp. 70-75
Author(s):  
Lionella Palego ◽  
Annalisa Giromella ◽  
Maria Rosa Mazzoni ◽  
Antonio Giuseppe Naccarato ◽  
Donatella Marazziti
Keyword(s):  
Human Brain ◽  
Adenylyl Cyclase ◽  
Mood Disorders ◽  
Present Article ◽  
Preliminary Data ◽  
Second Messenger ◽  
Cyclase Activity ◽  
Adenylyl Cyclase Activity ◽  
The Past ◽  
Second Messenger Pathways

AbstractDuring the past decade, an increasing interest has been shifted from the study of neuroreceptors to their links with second-messenger pathways. In the present article, we shall briefly review the methodological tools for evaluating adenylyl cyclase activity in several human brain and peripheral models, as well as the studies suggesting its involvement in the pathophysiology of mood disorders. We shall present also some preliminary data obtained in our laboratory providing evidence for the measurement of serotonin-sensitive adenylyl cyclase activity in human brain postmortem.

Adenylyl Cyclase Activity in Postmortem Human Brain: Evidence of Altered G Protein Mediation in Alzheimer's Disease

1992 ◽  
Vol 58 (4) ◽  
pp. 1409-1419 ◽  
Author(s):  
Richard F. Cowburn ◽  
Cora O'Neill ◽  
Rivka Ravid ◽  
Irina Alafuzoff ◽  
Bengt Winblad ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Human Brain ◽  
Adenylyl Cyclase ◽  
G Protein ◽  
Cyclase Activity ◽  
Adenylyl Cyclase Activity ◽  
Postmortem Human Brain

Effects of postmortem delay on serotonin and (+)8-OH-DPAT-mediated inhibition of adenylyl cyclase activity in rat and human brain tissues

1999 ◽  
Vol 816 (1) ◽  
pp. 165-174 ◽  
Author(s):  
Lionella Palego ◽  
Annalisa Giromella ◽  
Donatella Marazziti ◽  
Franco Borsini ◽  
Antonio Giuseppe Naccarato ◽  
...  
Keyword(s):  
Human Brain ◽  
Adenylyl Cyclase ◽  
Cyclase Activity ◽  
Adenylyl Cyclase Activity ◽  
Brain Tissues

Dopamine D1-stimulated adenylyl cyclase activity in cerebral cortex of autopsied human brain

2001 ◽  
Vol 39 (2) ◽  
pp. 117-125 ◽  
Author(s):  
Junchao Tong ◽  
Brian M. Ross ◽  
Allan L. Sherwin ◽  
Stephen J. Kish
Keyword(s):  
Cerebral Cortex ◽  
Human Brain ◽  
Adenylyl Cyclase ◽  
Cyclase Activity ◽  
Adenylyl Cyclase Activity

Characterization and regional distribution of adenylyl cyclase activity from human brain

1991 ◽  
Vol 18 (3) ◽  
pp. 389-398 ◽  
Author(s):  
Richard F. Cowburn ◽  
Anita Garlind ◽  
Cora O'Neill ◽  
Irina Alafuzoff ◽  
Bengt Winblad ◽  
...  
Keyword(s):  
Human Brain ◽  
Adenylyl Cyclase ◽  
Regional Distribution ◽  
Cyclase Activity ◽  
Adenylyl Cyclase Activity

Clozapine effects on adenylyl cyclase activity and serotonin type 1A receptors in human brain post-mortem

2014 ◽  
Vol 28 (4) ◽  
pp. 320-328 ◽  
Author(s):  
Donatella Marazziti ◽  
Stefano Baroni ◽  
Lionella Palego ◽  
Laura Betti ◽  
Gino Giannaccini ◽  
...  
Keyword(s):  
Human Brain ◽  
Adenylyl Cyclase ◽  
Cyclase Activity ◽  
Post Mortem ◽  
Adenylyl Cyclase Activity

scholarly journals Region-dependent effects of flibanserin and buspirone on adenylyl cyclase activity in the human brain

2002 ◽  
Vol 5 (02) ◽  
Author(s):  
Donatella Marazziti ◽  
Lionella Palego ◽  
Annalisa Giromella ◽  
Maria Rosa Mazzoni ◽  
Franco Borsini ◽  
...  
Keyword(s):  
Human Brain ◽  
Adenylyl Cyclase ◽  
Cyclase Activity ◽  
Adenylyl Cyclase Activity

Calcium Entry Attenuates Adenylyl Cyclase Activity

CHEST Journal ◽  
1995 ◽  
Vol 107 (5) ◽  
pp. 1420-1425 ◽  
Author(s):  
William B. Abernethy ◽  
John F. Butterworth ◽  
Richard C. Prielipp ◽  
Jian P. Leith ◽  
Gary P. Zaloga
Keyword(s):  
Adenylyl Cyclase ◽  
Calcium Entry ◽  
Cyclase Activity ◽  
Adenylyl Cyclase Activity
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