Ricerche genetiche sulle neoplasie dell'utero

1958 ◽  
Vol 7 (1) ◽  
pp. 47-90 ◽  
Author(s):  
Beolchini Pier Emilio ◽  
Cresseri Angelo ◽  
Gianferrari Luisa Malcovati Piero ◽  
Morganti Giuseppe
Keyword(s):  
Cervix Uteri ◽  
Control Material ◽  
Familial Incidence ◽  
Unselected Sample ◽  
Cancer Of The Cervix

SUMMARYThe Authors refer the results of the genetical research on 199 probands with cancer of the cervix uteri (unselected sample of the 418 collected cases). In comparison with a suitable control material a significant higher familial incidence does not result.

Ricerche genetiche sulle neoplasie dell'utero

1956 ◽  
Vol 5 (3) ◽  
pp. 362-368
Author(s):  
Beolchini Pier Emilio ◽  
Cresseri Angelo ◽  
Gianferrari Luisa ◽  
Malcovati Piero ◽  
Morganti Giuseppe
Keyword(s):  
Critical Review ◽  
Statistical Data ◽  
Uterine Cancer ◽  
Cervix Uteri ◽  
Review Of The Literature ◽  
Familial Incidence ◽  
Cancer Of The Cervix

SUMMARYThe Authors after a brief critical review of the literature on the familial incidence of uterine cancer, refer some clinical and statistical data of the 144 cases of cancer of the corpus and of the 418 cases of cancer of the cervix uteri that have been collected during their work.

CANCER OF THE CERVIX UTERI: SYDNEY HOSPITAL FIGURES FOR FIFTEEN, TEN AND FIVE YEAR PERIODS FROM 1929 TO 1943

1950 ◽  
Vol 2 (8) ◽  
pp. 277-281
Author(s):  
H. K. Porter ◽  
A. R. H. Duggan ◽  
S. D. Bray ◽  
R. S. Ford
Keyword(s):  
Cervix Uteri ◽  
Cancer Of The Cervix

DETECTION OF CANCER OF THE CERVIX UTERI

1950 ◽  
Vol 5 (6) ◽  
pp. 879-880
Author(s):  
H. E. NIEBURGS ◽  
EDGAR R. PUND
Keyword(s):  
Cervix Uteri ◽  
Cancer Of The Cervix

Improved control of invasive cervical cancer in Sweden over six decades by earlier clinical detection and better treatment.

1995 ◽  
Vol 13 (3) ◽  
pp. 715-725 ◽  
Author(s):  
P Sparén ◽  
L Gustafsson ◽  
L G Friberg ◽  
J Pontén ◽  
R Bergström ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Invasive Cervical Cancer ◽  
Local Treatment ◽  
Substantial Reduction ◽  
External Beam Radiation ◽  
Cervix Uteri ◽  
Beam Radiation ◽  
Clinical Detection ◽  
Cancer Of The Cervix ◽  
Incident Cases

PURPOSE Cancer of the cervix uteri can be controlled by cytologic screening for the detection of precursor lesions, but such intervention remains unrealistic in many countries in which this cancer is common. The possibility of reducing mortality by earlier clinical detection, followed by basic therapy, has never been properly assessed. PATIENTS AND METHODS We compiled records of incident cases of invasive cancer of the cervix diagnosed in a defined area of Sweden from 1930 through 1990. In a cohort of 6,044 women, we analyzed temporal trends in incidence and survival by clinical stage and age at diagnosis. Generalized proportional hazards models were used to study several factors simultaneously and quantify the overall reduction in mortality. RESULTS For each successive stage at diagnosis, the overall risk of dying increased 2.5-fold (95% confidence interval [CI], 2.4 to 2.7). From 1930, a marked improvement in stage distribution was accompanied by increasing survival rates in stages I and II disease. These changes largely took place before the introduction of screening and external-beam radiation. The 10-year relative survival rate increased from 33% in the 1930s to approximately 55% in the 1950s and thereafter. CONCLUSION Improvements in public and professional awareness of cervical cancer resulted in diagnoses at earlier clinical stages. The rate of cure in early stages improved when basic local treatment was introduced, but only little of the progress was attributable to the introduction of more advanced treatment technologies. These findings offer considerable hope for a substantial reduction in the mortality of cervical cancer without cytologic screening, even in countries with limited resources.

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