Role of stereotactic radiosurgery in the management of single or multiple cerebral metastases

2003 ◽  
Vol 3 (4) ◽  
pp. 197-203
Author(s):  
K. Hickey
1998 ◽  
Vol 5 (2) ◽  
pp. 124-129 ◽  
Author(s):  
Frederick F. Lang ◽  
David M. Wildrick ◽  
Raymond Sawaya

Background: Metastatic brain tumors represent the most common neurological complication in patients with systemic cancer. They are predominantly cerebrally located and constitute a significant source of morbidity and mortality. The overall incidence of brain metastases exceeds that of all other intracranial tumors, and as improved systemic cancer treatments have extended patients’ lives, this number is rising. Methods: The role of surgery in the management of cerebral metastases is reviewed by considering patient selection criteria, surgical approaches to metastases, intraoperative adjuncts, whole-brain irradiation as a postoperative adjuvant, resection of multiple vs single metastases, and the relative roles of stereotactic radiosurgery and conventional surgery. Results: Surgical resection of single or multiple metastases can be effective management for patients with otherwise good prognoses, providing all the known metastases can be removed without producing significant neurologic deficit. Radiosurgery, an alternate approach, can be used for smaller or inaccessible tumors. Conclusions: The presence of multiple brain metastases does not automatically contraindicate surgery because in properly selected patients, resection of multiple metastases can extend survival and enhance the quality of life. An awareness of how the modalities of open craniotomy, whole-brain radiotherapy, and stereotactic radiosurgery best complement each other will result in the best outcomes.


2016 ◽  
Vol 119 ◽  
pp. S539
Author(s):  
H. Benghiat ◽  
A. Hartley ◽  
A. Kapadia ◽  
G. Heyes ◽  
P. Sanghera

2018 ◽  
Vol 14 (1) ◽  
pp. 55-67
Author(s):  
Jacob A. Miller ◽  
Ehsan H. Balagamwala ◽  
Samuel T. Chao

2004 ◽  
Vol 69 (1-3) ◽  
pp. 319-334 ◽  
Author(s):  
Jack P. Rock ◽  
Samuel Ryu ◽  
Fang-Fang Yin ◽  
Faye Schreiber ◽  
Muwaffak Abdulhak

Author(s):  
Hideyuki Kano ◽  
Ajay Niranjan ◽  
Douglas Kondziolka ◽  
John C. Flickinger ◽  
Dade Lunsford

2003 ◽  
Vol 14 (5) ◽  
pp. 1-5 ◽  
Author(s):  
Steven D. Chang ◽  
Gordon T. Sakamoto

Object Hemangiopericytomas represent a small subset of meningeal tumors. Despite their relatively uncommon nature, they are aggressive tumors known for recurrence. Resection is the standard treatment in most, although regrowth and metastases are common even after resection. The authors evaluate the role of stereotactic radiosurgery in the treatment of recurrent hemangiopericytomas. Methods In a review of the Stanford radiosurgery patient database between 1989 and 2002, the authors found eight patients with recurrent hemangiopericytoma who underwent stereotactic radiosurgery. The mean age of this population was 45.1 years (range 24–67 years). All patients had been previously treated with resection, and five patients (63%) had undergone conventional radiotherapy. The mean radiosurgery dose to the tumor margin was 20.5 Gy (range 16–24 Gy). The mean clinical and radiographic follow-up period was 44 months (range 8–77 months). Of the eight tumors treated with radiosurgery, six decreased in size and two ultimately progressed. There were no radiosurgery-related complications. Conclusions Stereotactic radiosurgery of hemangiopericytomas can result in increased tumor control and should be considered as a treatment option for patients in whom the diagnosis has been established and in whom residual tumor is demonstrated postoperatively. Close clinical and radiographic follow-up evaluation is necessary in this patient population because of the high rate of local recurrence and distant metastases.


2015 ◽  
Vol 17 (suppl 5) ◽  
pp. v46.2-v46
Author(s):  
Deborah Marshall ◽  
Logan Marcus ◽  
Brandon McCutcheon ◽  
Steve Goetsch ◽  
John Alksne ◽  
...  

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