A new approach to cancer treatment

2014 ◽  
Vol 14 (1) ◽  
pp. 99-101 ◽  
Author(s):  
Syed F. Akber
Keyword(s):  
Radiation Treatment ◽  
Lattice Relaxation ◽  
Lattice Relaxation Time ◽  
Proton Spin ◽  
Ionising Radiation ◽  
Spin Lattice Relaxation ◽  
Water Proton ◽  
New Approach ◽  
Spin Lattice

AbstractA new approach is applied to correlate different phases of the HeLa cell S-3 with mean lethal ionising radiation dose (Do) along with nuclear magnetic resonance water-proton spin-lattice relaxation time (T1). This information can be used to pin-point the mitotic phase of the cells in vivo. This enables us to apply ionising radiation treatment at that particular time. This will increase the efficacy of radiation treatment in cancer patients.

Surface Induced Spin-Lattice Relaxation of Water in Tricalcium Silicate Gels

1991 ◽  
Vol 46 (8) ◽  
pp. 697-699
Author(s):  
F. Milia ◽  
Y. Bakopoulos ◽  
Lj. Miljkovic
Keyword(s):  
Grain Size ◽  
Lattice Relaxation ◽  
Lattice Relaxation Time ◽  
Tricalcium Silicate ◽  
Proton Spin ◽  
Spin Lattice Relaxation ◽  
Water Proton ◽  
Hydration Time ◽  
Spin Lattice ◽  
Stage Process

AbstractThe water proton spin-lattice relaxation time and recovery function of exchangeable water was measured in tricalcium silicate (C3S) gels. The measurements were carried out as a function of the hydration time and grain size. Results show that the hydration of (C3S) is a two stage process. A model is developped

NMR water-proton spin-lattice relaxation time of human red blood cells and red blood cell suspensions

FEBS Letters ◽  
1988 ◽  
Vol 234 (2) ◽  
pp. 349-352 ◽  
Author(s):  
Stephen Gene Sullivan ◽  
Arnold Stern ◽  
Jesse S. Rosenthal ◽  
Lawrence A. Minkoff ◽  
Arnold Winston
Keyword(s):  
Relaxation Time ◽  
Blood Cell ◽  
Blood Cells ◽  
Lattice Relaxation ◽  
Lattice Relaxation Time ◽  
Proton Spin ◽  
Spin Lattice Relaxation ◽  
Water Proton ◽  
Spin Lattice ◽  
Human Red Blood Cells

A novel approach to assess mean lethal radiation dose with water proton spin lattice relaxation times

2010 ◽  
Vol 10 (2) ◽  
pp. 117-119
Author(s):  
Syed F. Akber ◽  
Than S. Kehwar
Keyword(s):  
Relaxation Time ◽  
Radiation Dose ◽  
Lattice Relaxation ◽  
Lattice Relaxation Time ◽  
Proton Spin ◽  
Spin Lattice Relaxation ◽  
Proton Nuclear Magnetic Resonance ◽  
Water Proton ◽  
Spin Lattice Relaxation Time ◽  
Spin Lattice

AbstractThe assessment of mean lethal radiation dose (D0) in human organs, using multi-target and linear quadratic models, with water proton nuclear magnetic resonance spin lattice relaxation time yields a correlation coefficient of 0.90 and 0.82, respectively. Results of this study reveal that as the spin lattice relaxation time increases, the D0 decreases.

Role of Paramagnetic Ions and Water Proton Spin-Lattice Relaxation Time in Biological Systems

1993 ◽  
Vol 32 (01) ◽  
pp. 52-56 ◽  
Author(s):  
S. F. Akber
Keyword(s):  
Relaxation Times ◽  
Lattice Relaxation ◽  
Lattice Relaxation Time ◽  
Proton Spin ◽  
Spin Lattice Relaxation ◽  
Manganese Concentration ◽  
Water Proton ◽  
Manganese Ion ◽  
Spin Lattice ◽  
Paramagnetic Ions

SummaryThis paper summarizes the observations of different studies concerning the influence of paramagnetic ions on spin-lattice relaxation times in magnetic resonance imaging. Based on findings that manganese ion content in cancer tissues is decreased in comparison to normal tissues, the results of different papers analysing the influence of tissue manganese concentration on spin- lattice relaxation times are collected and compared. Neither the comparison between different organs, different animals nor the comparison between different tissues (normal and malignant) showed correlations of practical consequences between manganese concentrations and spin-lattice relaxation times. These results are consistent with those from studies with copper and iron ions in living systems.

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