A Nonempirical Method Using LC/MS for Determination of the Absolute Configuration of Constituent Amino Acids in a Peptide:  Elucidation of Limitations of Marfey's Method and of Its Separation Mechanism

1997 ◽  
Vol 69 (16) ◽  
pp. 3346-3352 ◽  
Author(s):  
Kiyonaga Fujii ◽  
Yoshitomo Ikai ◽  
Tsuyoshi Mayumi ◽  
Hisao Oka ◽  
Makoto Suzuki ◽  
...  
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Separation Mechanism ◽  
Nonempirical Method ◽  
The Absolute

scholarly journals Rapid Organocatalytic Chirality Analysis of Amines, Amino Acids, Alcohols, Amino Alcohols and Diols with Achiral Iso(thio)cyanate Probes

2021 ◽  
Author(s):  
Eryn Nelson ◽  
Jeffrey S. S. K. Formen ◽  
Christian Wolf
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Rapid Determination ◽  
Amino Alcohols ◽  
Enantioselective Synthesis ◽  
Widespread Occurrence ◽  
Chiral Compounds ◽  
New Methods ◽  
The Absolute

The widespread occurrence and significance of chiral compounds does not only require new methods for their enantioselective synthesis but also efficient tools that allow rapid determination of the absolute configuration,...

Determination of the Absolute Configuration of Amines and α-Amino Acids by1H NMR of (R)-O-Aryllactic Acid Amides†

1996 ◽  
Vol 61 (21) ◽  
pp. 7285-7290 ◽  
Author(s):  
Rafael Chinchilla ◽  
Larry R. Falvello ◽  
Carmen Nájera
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
The Absolute

Simultaneous detection and determination of the absolute configuration of thiazole-containing amino acids in a peptide

Tetrahedron ◽  
2002 ◽  
Vol 58 (34) ◽  
pp. 6873-6879 ◽  
Author(s):  
Kiyonaga Fujii ◽  
Yukie Yahashi ◽  
Tomoyo Nakano ◽  
Susumu Imanishi ◽  
Susana F Baldia ◽  
...  
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Simultaneous Detection ◽  
The Absolute

Determination of the Complete Absolute Configuration of Petriellin A

2006 ◽  
Vol 59 (6) ◽  
pp. 407 ◽  
Author(s):  
Luigi Aurelio ◽  
Robert T. C. Brownlee ◽  
Jason Dang ◽  
Andrew B. Hughes ◽  
Gideon M. Polya
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Natural Product ◽  
Absolute Configuration ◽  
Structural Determination ◽  
Amino Acid Residues ◽  
The Common ◽  
The Absolute ◽  
Derivatives Of

We report the full structural determination of the depsipeptide petriellin A. The absolute configuration of the amino acid residues, N-methyl isoleucine and N-methyl threonine, have been determined by a combination of HPLC and TLC comparison of synthetic Marfey’s derivatives and Marfey’s derivatives of the natural product hydrolysate. The configuration of the chiral centres in these two N-methylated residues was found to be the same as those of the common unmethylated l-amino acids.

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